Recovery of Serum Creatinine at Discharge Impacts Mortality

Kidney; Functional Disturbance Clinical Trial

— RECOST  

Official title:

Recovery of Serum Creatinine at Discharge Impacts Mortality, Long-term and Short-term

Clinical Trial Details — Status: Active, not recruiting

Administrative data

• NCT number: NCT03417791
• Other study ID #: GDREC2017296H
• Status: Active, not recruiting
• Phase: N/A
• First received: January 17, 2018
• Last updated: January 24, 2018
• Start date: January 1, 2007
• Est. completion date: December 30, 2018

Study information

• Verified date: November 2017
• Source: Guangdong General Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The aim of our study is to assess the mortality in the in-hospital patients who have elevated serum creatinine. A registry of patients with increased serum creatinine during hospital was conducted at the Guangdong General Hospital from January 1st, 2007 to December 30th, 2013. The primary clinical outcome is all-cause mortality, followed from the date of hospital discharge to Dec 30th 2018. Patients were divided into three groups, according to the serum creatinine recovery ratio (discharge/max serum creatinine). All-cause mortality, including the date of death, was identified from the electronic hospitalization data, phone follow-up, and confirmed by the household registration (HUKOU) system, a record of registration required by law in China. Baseline characteristics, including primary disease diagnosis, blood pressure, major treatment, drug use and et al, were collected. Demographic data were collected from the electronic hospitalization data and electronic hospital discharge records. All co-morbid conditions were identified using International Statistical Classification of Diseases, Tenth Revision (ICD-10), coding algorithms applied to electronic physician claims and electronic hospital discharge records.

Recruitment information / eligibility

• Status: Active, not recruiting
• Enrollment: 20000
• Est. completion date: December 30, 2018
• Est. primary completion date: December 30, 2018
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• In-hospital patients in Guangdong General Hospital in 2007

• Age>=18y

• Patients with increased serum creatinine during hospital

Exclusion Criteria:

• Death during hospital

• Diagnosed with End-stage renal disease

• given the renal replace therapy during hospital

Related Conditions & MeSH terms

• Kidney; Functional Disturbance
• Pathologic Processes

Intervention

Other:
• no intervention
no intervention

Locations

Country	Name	City	State
China	Guangdong General Hospital	Guangzhou	Guangdong

Sponsors (1)

Lead Sponsor	Collaborator
Guangdong General Hospital

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	all-cause mortality	all-cause mortality	10 years