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NCT00172302 Clinical Trial

Can Intravenous Vitamin C Improve Skin Hyperpigmentation in Long-Term Hemodialysis Patients?

Kidney Failure, Chronic Clinical Trial

Official title:
Can Intravenous Vitamin C Improve Skin Hyperpigmentation in Long-Term Hemodialysis Patients?

Clinical Trial Details — Status: Not yet recruiting

Administrative data
NCT number NCT00172302
Other study ID # 930105
Secondary ID
Status Not yet recruiting
Phase N/A
First received September 12, 2005
Last updated September 12, 2005
Start date November 2005

Study information
Verified date May 2005
Source National Taiwan University Hospital
Contact n/a
Is FDA regulated No
Health authority Taiwan: Department of Health
Study type Interventional

Clinical Trial Summary

Intravenous vitamin C may improve skin hyperpigmentation in chronic hemodialysis patients

Description:

Melanogenesis is caused by enzymatic conversion of tyrosine to melanin pigments.Ascorbic acid has the ability to inhibit peroxidase and may thus inhibit melanin synthesis.

Recruitment information / eligibility
Status Not yet recruiting
Enrollment 40
Est. completion date
Est. primary completion date
Accepts healthy volunteers No
Gender Both
Age group 20 Years to 80 Years
Eligibility Inclusion Criteria:

- chronic hemodialysis patients

Exclusion Criteria:

- allergic to vitamin C, using steroid, etc

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Double-Blind, Primary Purpose: Treatment

Related Conditions & MeSH terms

Intervention

Drug:
• vitamin C, intravenous injection

Locations
Country Name City State
Taiwan National Taiwan University Hospital Taipei

Sponsors (1)
Lead Sponsor Collaborator
National Taiwan University Hospital

Country where clinical trial is conducted

Taiwan, 

Outcome
Type Measure Description Time frame Safety issue
Primary Skin pigmentation extent
Secondary blood anti-oxidant level
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