China Kidney Patient Trials Network

Kidney Diseases Clinical Trial

— CKPTN  

Official title:

China Kidney Patient Trials Network

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05036850
• Other study ID #: CKPTN2019
• Status: Recruiting
• Start date: September 27, 2021
• Est. completion date: February 28, 2031

Study information

• Verified date: March 2023
• Source: George Clinical Pty Ltd
• Contact: FanHan Hsu
• Phone: +61 2 8052 4300
• Email: CKPTN[@]georgeclinical.com
• Is FDA regulated: No
• Study type: Observational [Patient Registry]

Clinical Trial Summary

This is a prospective multi-centre, observational cohort study of incident and prevalent patients diagnosed with a kidney disease in China.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 1200
• Est. completion date: February 28, 2031
• Est. primary completion date: September 15, 2026
• Accepts healthy volunteers: No
• Gender: All
• Age group: 2 Years and older

Eligibility

Inclusion Criteria:

1. Documented diagnosis of primary kidney disease

2. Regular visits (at least 6 monthly) with a physician at a participating site

3. eGFR > 15 ml/min/1.73 m2

4. = 2 years of age

5. Willing and able to sign informed consent

6. Willing to be approached about participation in interventional research studies

Exclusion Criteria:

• 1. Life-expectancy of less than 6 months

Related Conditions & MeSH terms

• Kidney Diseases

Locations

Country	Name	City	State
China	George Clinical (Beijing)	Beijing	Beijing

Sponsors (1)

Lead Sponsor	Collaborator
George (Beijing) Clinical Research Co. Ltd.

Country where clinical trial is conducted

China, 

References & Publications (7)

de Zeeuw D, Heerspink HJL, Jardine M, Perkovic V. Renal trials in diabetes need a platform: time for a global approach? Lancet Diabetes Endocrinol. 2018 May;6(5):356-358. doi: 10.1016/S2213-8587(17)30263-2. Epub 2017 Aug 7. No abstract available. — View Citation

Go AS, Chertow GM, Fan D, McCulloch CE, Hsu CY. Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. N Engl J Med. 2004 Sep 23;351(13):1296-305. doi: 10.1056/NEJMoa041031. Erratum In: N Engl J Med. 2008;18(4):4. — View Citation

Luyckx VA, Tonelli M, Stanifer JW. The global burden of kidney disease and the sustainable development goals. Bull World Health Organ. 2018 Jun 1;96(6):414-422D. doi: 10.2471/BLT.17.206441. Epub 2018 Apr 20. — View Citation

McGrogan A, Franssen CF, de Vries CS. The incidence of primary glomerulonephritis worldwide: a systematic review of the literature. Nephrol Dial Transplant. 2011 Feb;26(2):414-30. doi: 10.1093/ndt/gfq665. Epub 2010 Nov 10. — View Citation

Perkovic V, Craig JC, Chailimpamontree W, Fox CS, Garcia-Garcia G, Benghanem Gharbi M, Jardine MJ, Okpechi IG, Pannu N, Stengel B, Tuttle KR, Uhlig K, Levey AS. Action plan for optimizing the design of clinical trials in chronic kidney disease. Kidney Int Suppl (2011). 2017 Oct;7(2):138-144. doi: 10.1016/j.kisu.2017.07.009. Epub 2017 Sep 20. — View Citation

Strippoli GF, Craig JC, Schena FP. The number, quality, and coverage of randomized controlled trials in nephrology. J Am Soc Nephrol. 2004 Feb;15(2):411-9. doi: 10.1097/01.asn.0000100125.21491.46. — View Citation

Tonelli M, Muntner P, Lloyd A, Manns BJ, Klarenbach S, Pannu N, James MT, Hemmelgarn BR; Alberta Kidney Disease Network. Risk of coronary events in people with chronic kidney disease compared with those with diabetes: a population-level cohort study. Lancet. 2012 Sep 1;380(9844):807-14. doi: 10.1016/S0140-6736(12)60572-8. Epub 2012 Jun 19. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	eGFR (estimated Glomerular Filtration Rate)	Routine results	Collected six monthly, up to 5 years
Primary	Albuminuria	Routine results	Collected six monthly, up to 5 years