Kidney Cancer Clinical Trial
Official title:
Phase II Study of CC-5013 in Patients With Advanced Renal Cell Carcinoma (RCC)
RATIONALE: Lenalidomide may stop the growth of kidney cancer by blocking blood flow to the
tumor.
PURPOSE: This phase II trial is studying how well lenalidomide works in treating patients
with advanced or unresectable kidney cancer.
OBJECTIVES:
- Evaluate the best response in patients with advanced or unresectable renal cell
carcinoma (RCC) treated with lenalidomide.
- Evaluate the response duration, time to tumor progression, and survival of patients with
advanced RCC treated with lenalidomide.
- Evaluate the safety of this drug in these patients.
OUTLINE: This is an open-label study.
Patients receive oral lenalidomide daily on days 1-21. Courses repeat every 28 days in the
absence of unacceptable toxicity or disease progression.
After completion of study treatment, patients are followed every 3 months.
PROJECTED ACCRUAL: A total of 26 patients will be accrued for this study.
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