Ketosis Clinical Trial
Official title:
Effect of Ketone Supplementation on Glycogen Replenishment and Time Trial Performance Following Glycogen Lowering Exercise
20 healthy trained males will volunteer to participate in this study. there will be 2 treatments: Carbohydrate- ketone supplementation and carbohydrate alone. The purpose of this study is to evaluate the effect of glucose-ketone supplementation on a 20 km cycling time trial with a 2-hour feeding during a 4-hour recovery period following glycogen depleting exercise.
Status | Recruiting |
Enrollment | 20 |
Est. completion date | September 1, 2020 |
Est. primary completion date | September 1, 2020 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Male |
Age group | 18 Years to 40 Years |
Eligibility |
Inclusion Criteria: - In order to be eligible to participate in this study you must be a healthy male or female exercise trained individual (at least 1y training experience - at least 3x week), aged 18-40 years. Exclusion Criteria: - have not involved been involved in regular exercise (at least 3x week for at least the past year) - Have symptoms or take medication for respiratory, cardiovascular, metabolic, neuromuscular disease - Use any medications with side effects of dizziness, lack of motor control, or slowed reaction time - Are taking part in another research study - For women, if you are pregnant or become pregnant during the study. - Have a history of concussion/head injuries. - Have an excessive alcohol intake (>2 drinks/day) - Are a smoker |
Country | Name | City | State |
---|---|---|---|
Canada | Exercise Nutrition Laboratory (Western University) | London | Ontario |
Lead Sponsor | Collaborator |
---|---|
Western University, Canada |
Canada,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | 20 km cycling time trial | participants will ride for 20 km on a stationary bike and time to finish will be measured | 40 minutes | |
Secondary | Blood insulin | insulin in blood will be measured using ELISA kits | 2 hours | |
Secondary | Blood Lactate | blood lactate will be measured using lactate meter | 45 minutes | |
Secondary | Blood Ketones | Ketones in blood will be measured using ketone meter | 2 hours |
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT04477161 -
Effect of Ketone Esters in Parkinson's Disease
|
N/A | |
Active, not recruiting |
NCT05477368 -
Examining the Feasibility of Prolonged Ketone Supplement Drink Consumption in Adults With Type 2 Diabetes
|
N/A | |
Completed |
NCT04817176 -
MI-CBT Adherence Program for Lifestyle Interventions in Older Adults
|
Early Phase 1 | |
Completed |
NCT04565444 -
Ketones and Muscle Protein Synthesis
|
N/A | |
Not yet recruiting |
NCT06418074 -
Effects of Exogenous Ketosis on Renal Function, Renal Perfusion, and Sodium Excretory Capacity
|
N/A | |
Not yet recruiting |
NCT03954665 -
Ketone Supplementation and Exercise Performance
|
N/A | |
Active, not recruiting |
NCT06097754 -
Intermittent Exogenous Ketosis (IEK) at High Altitude
|
N/A | |
Terminated |
NCT03790436 -
Betaquik as an Adjunct to Dietary Management of Epilepsy in Adults on the Modified Atkins Diet
|
N/A | |
Completed |
NCT03299543 -
Comparison Between Breath Acetone and Blood Beta-Hydroxybutyrate
|
||
Not yet recruiting |
NCT03659825 -
Ketone Esters for Optimization of Cognitive Performance in Hypoxia
|
N/A | |
Active, not recruiting |
NCT04156477 -
Markers of Appetite Regulation During Exogenous Ketosis
|
N/A | |
Completed |
NCT04130724 -
Characterization of a Portable Solid-State Breath Acetone Testing Device for Real-Time Ketosis Status
|
||
Recruiting |
NCT04594265 -
Weight-Adjusted Dosing of 3-OHB in Patients With Chronic Heart Failure
|
Phase 2 | |
Not yet recruiting |
NCT04576026 -
Exogenous Ketone Supplementation and Cognitive Function During Exercise
|
N/A | |
Completed |
NCT05558488 -
The Effect of a Meatless,Keto Restrictive Diet on Body Composition,Strength Capacity,Oxidative Stress,Immune Response
|
N/A | |
Recruiting |
NCT03564002 -
Metabolic Effects of Very Low Carbohydrate Ketogenic Diet in Subjects With Severe Obesity
|
||
Completed |
NCT04309214 -
Market Research - Acceptability Study for New MCT Fat Products
|
N/A | |
Completed |
NCT05588427 -
Effect of Ketone Ester Supplementation on Hypoxic Tolerance
|
N/A | |
Recruiting |
NCT05656339 -
Metabolic Effects of Whey Protein Supplementation After Fasting in Volunteers
|
N/A | |
Active, not recruiting |
NCT04737694 -
Ketone Supplements and Substrate Oxidation and Physical Performance
|
N/A |