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Topography Versus Non-Topography-Guided PRK With CXL in Keratoconus — keratoconus  

Keratoconus Clinical Trial

Official title:
Topography Versus Non-Topography-Guided Photorefractive Keratectomy With Corneal Cross-Linking Variations in Keratoconus

Clinical Trial Summary

To our knowledge, this study is one of the first to compare the visual results of non-topography-guided and topography-guided photorefractive keratectomy (PRK) applying sequential and simultaneous corneal cross-linking (CXL) treatment for keratoconus. Considering recent advances in cross-linking and imaging in keratoconus, the outcomes of this study can lead us to several non-invasive algorithm management options.

Clinical Trial Description

Interventional and comparative prospective study: Sixty-nine eyes (38 patients) suffering from keratoconus (stages 1-2 Amsler-Krumeich classification) were divided into four groups. The four groups underwent topography- and non-topography-guided PRK with sequential and simultaneous CXL. The main outcome measures were pre- and postoperative uncorrected distance visual acuity (UDVA), best corrected distance visual acuity (CDVA), manifest refraction, contrast sensitivity, and keratometry. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03890718
Study type Interventional
Source Shahid Beheshti University
Contact
Status Enrolling by invitation
Phase N/A
Start date March 30, 2017
Completion date December 15, 2023
View Details
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