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Corneal Sensitivity Cross-linking Keratoconus — CSK  

Keratoconus Clinical Trial

Official title:
Corneal Sensitivity Changes Following Cross-linking for Progressive Lower Stage Keratoconus

Clinical Trial Summary

To evaluate corneal sensitivity changes following corneal cross-linking (CXL) in patients with progressive lower stage keratoconus.

Clinical Trial Description

Thirty eight eyes of 19 patients (11 women, 8 men) were included in a prospective, nonrandomized clinical study. Mean patient age was 22 years (range, 18-26 years). Inclusion criteria were low stage bilateral progressive keratoconus, transparent cornea and thinnest corneal thickness ≥ 440 µm. Using the Cochet-Bonnet esthesiometer central corneal sensitivity was measured preoperatively, after 7 days, and once a month after surgery until recovery of the baseline preoperative level. Normal levels of central corneal sensitivity were considered above 40mm. ;

Study Design

Endpoint Classification: Safety Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01743443
Study type Interventional
Source Instituto de Olhos de Goiania
Contact
Status Completed
Phase Phase 2/Phase 3
Start date March 2009
Completion date October 2012
View Details
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