Keratoconjunctivitis Sicca Clinical Trial
Official title:
A Single-Center Study Evaluating the Effect of the Controlled Adverse Environment (CAE) on Tear Film Stability Using the OPI 2.0 System, Ocular Protection Index (OPI), Tear Film Break-Up Time (TFBUT) and Mean Break up Area by Region (MBA) in Patients Diagnosed With Dry Eye Evaluated During Their Natural Blink Pattern
The purpose of this study is to evaluate the effect of the controlled adverse environment (CAE) on Mean Break-Up Area in subjects diagnosed with Dry Eye Syndrome.
Single-Center, Pilot, controlled adverse environment (CAE) Study.
This is a single-center, one visit, pilot, CAE study. Dry Eye Subjects (N=30) who qualify
will undergo tear film video recording, fluorescein staining, and break up time before CAE
exposure and after CAE exposure.
All subjects will undergo baseline dry eye assessments including fluorescein staining,
breakup time, conjunctival redness and tear film video recording. Subjects who qualify will
then undergo CAE exposure for 90 minutes. At the end of CAE exposure subjects will undergo
dry eye assessments again.
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Observational Model: Case-Only, Time Perspective: Cross-Sectional
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