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Keratoconjunctivitis Sicca clinical trials

View clinical trials related to Keratoconjunctivitis Sicca.

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NCT ID: NCT06329687 Terminated - Dry Eye Clinical Trials

A Study Evaluating the Safety of the Nasal Pump

Start date: February 21, 2024
Phase: Phase 4
Study type: Interventional

The objective of this study is to determine the safety of the Tyrvaya nasal pump.

NCT ID: NCT05629364 Terminated - Dry Eye Disease Clinical Trials

A Multi-Centre, Randomised, Controlled, Masked Phase 2 Study of the Safety and Efficacy of KIO-101 Ophthalmic Solution, Versus Vehicle Control in the Treatment of Dry Eye Disease in Patients With Autoimmune Disease

Start date: March 15, 2023
Phase: Phase 2
Study type: Interventional

A Multi-Centre, Randomised, Controlled, Masked Phase 2 Study of the Safety and Efficacy of KIO-101 Ophthalmic Solution, versus Vehicle Control in the treatment of Dry Eye Disease in Patients with Autoimmune Disease

NCT ID: NCT05053789 Terminated - Eye Diseases Clinical Trials

Efficacy of Different Treatment Regimens With Chitosan-N- Acetylcysteine in Moderate-to-severe Dry Eye Disease

Start date: May 12, 2021
Phase: N/A
Study type: Interventional

Aim of this pilot study is to evaluate the best treatment regime of Chitosan-N-Acetylcysteine (Lacrimera®) compared to preservative-free, Hyaluronic-acid containing eyedrops (Hylo-Vision® sine).

NCT ID: NCT04498468 Terminated - Dry Eye Clinical Trials

Safety and Efficacy of Dexamethasone Ophthalmic Insert (Dextenza®) in the Management of Clinically Significant Dry Eye

Start date: March 16, 2021
Phase: Phase 4
Study type: Interventional

To determine efficacy and safety profile of dexamethasone 0.4mg lacrimal insert in dry eye related ocular surface inflammation.

NCT ID: NCT04413253 Terminated - Dry Eye Syndromes Clinical Trials

Xiidra vs. Xiidra + Dextenza Treatment for Dry Eye Disease

Start date: August 1, 2020
Phase: Phase 4
Study type: Interventional

To evaluate the benefit of treatment with a physician administered intracanalicular dexamethasone insert in patients with dry eye who are beginning treatment with Xiidra (lifitegrast ophthalmic solution) to reduce the signs and symptoms of dry eye disease.

NCT ID: NCT04260893 Terminated - Dry Eye Clinical Trials

Prospective Study To Assess The Safety And Effectiveness Of Tixel Treatment On Dry Eye Symptoms In Asian Patients

DED
Start date: January 23, 2020
Phase: N/A
Study type: Interventional

Pilot study where effect of standard Tixel treatment as used for periorbital wrinkles would be assessed on Dry Eye Disease symptoms and signs in Asian Patients.

NCT ID: NCT04159935 Terminated - Dry Eye Clinical Trials

Investigating iLux Efficacy in Contact Lens Wearers With Evaporative Dry Eye Disease

SHEEPDOG
Start date: November 15, 2019
Phase: Phase 4
Study type: Interventional

The purpose of this clinical trial is to investigate the efficacy of a single iLux® treatment in symptomatic CL wearers who have DED (according to the TFOS DEWS II diagnostic criteria), of the evaporative dry eye disease subtype (EDE).

NCT ID: NCT04143841 Terminated - Dry Eye Syndromes Clinical Trials

Viveye Ocular Magnetic Neurostimulation System (OMNS) for the Management of Severe Dry Eye Disease

OMNS
Start date: October 30, 2019
Phase: N/A
Study type: Interventional

The objective of this study is to evaluate the safety and effectiveness of Viveye OMNS non-invasive treatment for management of the signs and symptoms of severe dry eye disease.

NCT ID: NCT04015219 Terminated - Dry Eye Syndromes Clinical Trials

Management of Signs and Symptoms Associated With Dry Eye Disease

Start date: July 18, 2018
Phase: N/A
Study type: Interventional

A prospective randomized, and controlled study to compare the effectiveness of PROKERA® SLIM plus standard of care (SOC) in the PROKERA® SLIM Arm to SOC alone in the Control Arm. Subjects presenting with moderate DED defined as corneal fluorescein staining score of ≥ 3 points out of 9 will be recruited.

NCT ID: NCT03827564 Terminated - Dry Eye Syndromes Clinical Trials

Goblet Cell Degranulation Produced by Intranasal Tear Neurostimulator (ITN) in Dry Eye Disease

Start date: June 24, 2019
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate goblet cell degranulation following acute use of the Intranasal Tear Neurostimulator in participants with dry eye.