Keloid Clinical Trial
Official title:
Fractional Laser Assisted Steroid Therapy vs Intralesional Steroids in the Treatment of Keloids
The purpose of this study is to compare the effects of fractional carbon dioxide (CO2) laser therapy immediately followed by intralesional steroid therapy against intralesional steroid therapy alone for the treatment of keloids.
Intralesional corticosteroids remain the gold standard treatment for keloids. However, more effective therapies are desperately desired. Ablative fractional laser (AFL) treatment facilitates delivery of intralesional steroid more deeply and uniformly into the skin by creating vertical channels. Recent studies have showed that fractional laser assisted steroid therapy can be effective in the treatment of keloids. However the studies are lacking in comparing this treatment modality to the gold standard of intralesional steroids. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT02923596 -
Retrospective Study of Keloid Disorder
|
N/A | |
Completed |
NCT02922972 -
Treatment of Keloid Scar by Autologous Platelet Rich Plasma Obtained With RgenKit-BCT
|
N/A | |
Terminated |
NCT01478243 -
Study of Psycho-Social Impact of Keloid
|
N/A | |
Recruiting |
NCT01423383 -
Epidemiology Study of Keloid
|
N/A | |
Completed |
NCT03228693 -
Gene Expression and Biomarker Profiling of Keloid Skin
|
N/A | |
Not yet recruiting |
NCT04326959 -
Implantation of Mesenchymal Stem Cell, Conditioned Medium, or Triamcinolone Acetonide for Keloid
|
Phase 1/Phase 2 | |
Recruiting |
NCT03312166 -
Compressive Device to Prevent Keloïd Scars Recurrence [SCARWARS]
|
N/A | |
Recruiting |
NCT02823236 -
Efficacy of Intralesional Triamcinolone and 8% Topical Pirfenidone for Treatment of Keloid Scars
|
Phase 3 | |
Recruiting |
NCT04597060 -
The Safety and Efficacy of Thermo-mechanical System for Fractional Ablation Associated Triamcinolone Acetonide Drug Delivery for the Treatment of Hypertrophic Scars and Keloids
|
N/A | |
Completed |
NCT05887804 -
Comparison of Keloid Volume and Symptoms Reduction Between Intralesional Umbilical-Cord Mesenchymal Stem Cells, Its Conditioned Medium, and Triamcinolone Acetonide Injection as Keloid Therapy: A Randomised Controlled Trial
|
Phase 4 | |
Completed |
NCT05939817 -
The Effect of Intralesian Injection of Umbilical Cord Mesenchymal Stem Cells, Its Conditioned Medium, and Triamcinolone Acetonide on Type 1:3 Collagen Ratio and Interleukin-10 Levels in Keloid: A Randomised Controlled Trial
|
Phase 4 | |
Completed |
NCT03630198 -
Pain Outcomes Following Intralesional Corticosteroid Injections
|
Phase 4 | |
Completed |
NCT04169438 -
Pilot Study Investigating a Restorative Wound Care Cream Together With Petrolatum on Surgical Excisions
|
N/A | |
Recruiting |
NCT01423981 -
Web Based Investigation of Natural History of Keloid Disorder, an Online Survey
|
N/A | |
Completed |
NCT01446770 -
Evaluation of the Initial Safety and Efficacy of Keloid Lesions Treated With MF-4181
|
Phase 2 | |
Recruiting |
NCT06138964 -
Comparing the Effect of siSPARC Microneedle Patch Versus siSPARC+siLR4A Microneedle Patch on Post-surgical Scars
|
Phase 3 | |
Enrolling by invitation |
NCT05461157 -
Preoperative Silicone Ointment and Wound Healing
|
N/A | |
Not yet recruiting |
NCT04593706 -
Comparison of the Efficacy of Different Steroids in the Treatment of Abnormal Scars (Keloids, Hypertrophic Scars)
|
N/A | |
Active, not recruiting |
NCT04988022 -
Dupilumab in the Treatment of Keloids
|
Phase 4 | |
Withdrawn |
NCT02546076 -
Comparison of Dual-mode ER:YAG Laser in Patients With Long Keloid/Hypertrophic Scars
|
Phase 2 |