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Joint Disease clinical trials

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NCT ID: NCT01145157 Completed - Joint Disease Clinical Trials

A Comparison Between Signature Total Knee Arthroplasty (TKA) to Conventional TKA and Computer Assisted TKA

Start date: July 2010
Phase: N/A
Study type: Interventional

This is a prospective, randomised clinical outcomes study comparing the Signature Personalised Patient Care, Conventional Total Knee Arthroplasty and Computer Assisted Navigation, using Vanguard Knee System. The aim of the study is to evaluate the safety and efficacy of TKA using Signature Personalised Patient Care compared to Conventional TKA and Computer Assisted Navigation.

NCT ID: NCT00782197 Completed - Joint Disease Clinical Trials

Autologous Plasma Rich in Growth Factors (PRGF) Treating the Symptomatic Knee OA

Start date: January 2008
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of PRGF infiltrations in the treatment of knee osteoarthritis.

NCT ID: NCT00303056 Completed - Joint Disease Clinical Trials

Efficacy and Safety Study of Intra-articular Multiple Doses of Icatibant in Patients With Painful Knee Osteoarthritis

Start date: February 2006
Phase: Phase 2
Study type: Interventional

The primary objective is to compare the overall treatment effect on pain relief between icatibant and placebo. The secondary objectives are to assess the efficacy of icatibant in term of onset, extent and duration of pain relief relative to triamcinolone, to evaluate the safety of icatibant, to evaluate overall conditions of daily life after treatment with icatibant, to assess systemic exposure of icatibant following intra-articular injection.

NCT ID: NCT00223353 Completed - Joint Disease Clinical Trials

Quantitative Gait Analysis for Clinical Decision Making

Start date: November 1998
Phase: N/A
Study type: Observational

The overall purpose of this study is to develop an improved gait analysis system for the real time acquisition, calculation and interpretation of joint kinematic and kinetic information using linked segment body model animation to display and visually depict deviations from normal motion and joint function. Patients referred to the laboratory for clinical gait analysis are invited to participate in the project. If interested, subjects are informed by a study investigator of the study goals, procedures, risks and any benefits. A study investigator is responsible for obtaining informed consent. Data from normal subjects are used to establish a normative database. Data from other subjects contributes to the relevant databases of different disorders.