IVF Failure Clinical Trial
Official title:
Effect of Sildenafil Citrate on the Outcome of in Vitro Fertilization After Multiple IVF Failures Attributed to Poor Endometrial Development
| Verified date | February 2017 |
| Source | Ain Shams University |
| Contact | ahmed khairy, professor |
| Phone | 01090808047 |
| Is FDA regulated | No |
| Health authority | |
| Study type | Interventional |
The aim of this study is to evaluate the effect of sildenafil citrate on endometrial development in women with history of recurrent implantation failure after IVF
| Status | Recruiting |
| Enrollment | 80 |
| Est. completion date | August 10, 2017 |
| Est. primary completion date | August 1, 2017 |
| Accepts healthy volunteers | Accepts Healthy Volunteers |
| Gender | Female |
| Age group | 20 Years to 40 Years |
| Eligibility |
Inclusion Criteria: - (1) cases of infertility, older than 20 years of age and not older than 40 years. - (2) Body mass index (BMI):20-29. - (3) women have experienced two or more implantation failure attributed to inadequate endometrial development. Exclusion Criteria: - (1) Uterine abnormalities (e.g. septate, bicornuate and fibroid uterus, Asherman Syndrome). - (2) Any contraindication to sildenafil citrate or any of the components of its formulation including: - Concurrent use of organic nitrites and nitrates. - Severe hepatic impairment. - Severe renal impairment. - Hypotension. - Recent stroke or heart attack. |
| Country | Name | City | State |
|---|---|---|---|
| Egypt | Ain shams university | Cairo |
| Lead Sponsor | Collaborator |
|---|---|
| Ain Shams University |
Egypt,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | endometrial thickness measures | we will measure endometrial thickness by US in women with recurrent implantation failure | 21 days |