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Well-being in IBS: Strengths and Happiness (WISH)

Irritable Bowel Syndrome Clinical Trial

Official title:
The Well-being in IBS: Strengths and Happiness (WISH) Pilot Trial

Clinical Trial Summary

The purpose of this pilot study is to examine the feasibility, acceptability, and preliminary efficacy of a customized positive psychology (PP) intervention for patients with irritable bowel syndrome (IBS) compared to a wait list control group.

Clinical Trial Description

Irritable bowel syndrome (IBS), a disorder of gut-brain interaction (DGBI; formerly known as functional gastrointestinal disorder) is characterized by abdominal pain and altered bowel habits, and conceptualized as resulting from complex interactions between biological, psychological, and social factors. The treatment approach for IBS is multifaceted and focused on symptom reduction rather than cure. For mild or infrequent symptoms, lifestyle modification (e.g., diet and exercise), reassurance, and education about the disorder can at times be sufficient. For moderate to severe symptoms, a combination of pharmacotherapy and behavioral health interventions is often required. A growing body of evidence supports the use of behavioral health interventions to target the gut-brain axis in DGBI - aptly referred to as brain-gut behavior therapies (BGBT). Though highly effective, existing BGBT for IBS face important limitations including scalability and acceptability. There is also limited focus among existing BGBT on the promotion of positive psychological (PP) constructs (e.g., optimism), which are deficient in IBS, associated with fewer IBS symptoms, and associated with lower levels of distress in both clinical and non-clinical populations. PP interventions have successfully been implemented in a variety of other chronic medical conditions to improve well-being, health-related quality of life, and health behavior engagement. PP interventions are highly acceptable and easily delivered remotely without extensive specialized training, which increases their scalability and reach. As such, the investigators plan to do the following in this project: 1. Examine the feasibility and acceptability of a 9-week, telephone-delivered PP intervention adapted to the IBS population 2. Explore the impact of the PP intervention on psychological, behavioral, and health-related outcomes, compared to a wait list control group. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05289089
Study type Interventional
Source Massachusetts General Hospital
Contact
Status Completed
Phase N/A
Start date March 25, 2022
Completion date April 11, 2023
View Details
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