Irregular Astigmatism Clinical Trial
Official title:
Visual Outcomes of Topography Guided Photorefractive Keratectomy (PRK) for Treatment of Patients With Irregular Cornea
NCT number | NCT03140046 |
Other study ID # | PRK |
Secondary ID | |
Status | Completed |
Phase | N/A |
First received | |
Last updated | |
Start date | March 1, 2017 |
Est. completion date | March 1, 2018 |
Verified date | May 2020 |
Source | Assiut University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
Irregular astigmatism is one of the most serious and frequent complications of corneal
refractive surgery and one of the worst sequelae of other forms of corneal surgery . It is
also considered as one of common, serious complications of corneal injuries .
Spectacle correction is usually not useful in the correction of corneal irregular
astigmatism. Contact lenses represent a good alternative, but their adaptation and stability
are limited by the irregular corneal surface and patient discomfort.
In recent years, advancements in laser technology have offered better tools for dealing with
irregular astigmatism with finding new surgical methods to improve corneal regularity for the
correction of irregular astigmatism.
Topography-linked excimer laser is a potentially effective technique in the treatment of
irregular astigmatism after keratoplasty . In fact, customized ablation was shown to be an
effective means of treatment of irregular astigmatism due to different etiologies Such as
corneal Injuries , scar , or postoperative.
Some of the theoretical advantages of topography-driven photorefractive keratectomy (PRK) are
a better astigmatic correction, the possibility of correcting irregular astigmatism, and a
smaller ablation volume compared with standard treatments, resulting in better visual
performance.
Aim of the work To evaluate the efficacy, safety, and predictability of topography-guided
photorefractive keratectomy (PRK) to improve refractive status of patient with irregular
Cornea.
Status | Completed |
Enrollment | 20 |
Est. completion date | March 1, 2018 |
Est. primary completion date | March 1, 2018 |
Accepts healthy volunteers | No |
Gender | All |
Age group | N/A and older |
Eligibility |
Inclusion Criteria: - Patients with irregular corneal astigmatism caused by: - Trauma. - Non - Central Corneal Scars. - Previous corneal surgery. - With No other abnormalities in the eye. - Patient is willing to enter the study and sign a consent. Exclusion Criteria: - Patients with central corneal scars. - Patients with central haze interfering with visual acuity. - Patients with ectasia at corneal graft margins. - Patients with irregular astigmatism caused by corneal ectasia or keratoconus. - Patients had refractive surgery with ablations leaving a residual corneal thickness less than 250 µm. |
Country | Name | City | State |
---|---|---|---|
Egypt | Assiut University | Assiut |
Lead Sponsor | Collaborator |
---|---|
Assiut University |
Egypt,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Visual Acuity | The measure of the Visual Acuity and Best Corrected Visual acuity Using the Snellen Chart which give use an idea about visual acuity in Metric scale (e.g. 6\6 , 6\12) | follow up after 1 day, 1 week, 1 month and 3 months | |
Secondary | Refractive State | We will measure the Refractive state of the eye by using the Auto refractor which give us an idea about the refractive state in a Diopteric scale ( e.g. -2D , +4 D) . | follow up after 1 day, 1 week, 1 month and 3 months |
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