Iron Deficiency Anemia Clinical Trial
Official title:
Pilot Study for Investigation of the Feasibility and for Optimization of Oral Iron Substitution in the Course of Patient Blood Management for Orthopedic Surgery
Verified date | August 2018 |
Source | Kepler University Hospital |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
The aim of this pilot study is to investigate an 4 weeks period of oral iron substitution in the course of Patient Blood Management in preparation for orthopedic surgery.
Status | Terminated |
Enrollment | 20 |
Est. completion date | November 1, 2017 |
Est. primary completion date | November 1, 2017 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 55 Years and older |
Eligibility |
Inclusion Criteria: - age over 55 years - indication for patient blood management for elective orthopedic surgery - listed for a orthopedic surgery (e.g. hip or knee replacement) 5-7 weeks after begin of patient blood management - Haemoglobin male < 12-13g/dl, female <11-12g/dl - written informed consent after written and verbal information Exclusion Criteria: - indication for treatment with erythropoietin - pregnancy - nursing period - diarrhea or tendency to diarrhea - fructose intolerance - pre - menopause - permanent or expected blood loss - participation in other study - expected compliance problems - legal incapacity |
Country | Name | City | State |
---|---|---|---|
Austria | Kepler University Hospital | Linz |
Lead Sponsor | Collaborator |
---|---|
Kepler University Hospital |
Austria,
Danninger T, Rasul R, Poeran J, Stundner O, Mazumdar M, Fleischut PM, Poultsides L, Memtsoudis SG. Blood transfusions in total hip and knee arthroplasty: an analysis of outcomes. ScientificWorldJournal. 2014 Jan 21;2014:623460. doi: 10.1155/2014/623460. eCollection 2014. — View Citation
Gombotz H, Rehak PH, Shander A, Hofmann A. Blood use in elective surgery: the Austrian benchmark study. Transfusion. 2007 Aug;47(8):1468-80. — View Citation
Meybohm P, Richards T, Isbister J, Hofmann A, Shander A, Goodnough LT, Muñoz M, Gombotz H, Weber CF, Choorapoikayil S, Spahn DR, Zacharowski K. Patient Blood Management Bundles to Facilitate Implementation. Transfus Med Rev. 2017 Jan;31(1):62-71. doi: 10.1016/j.tmrv.2016.05.012. Epub 2016 May 28. Review. — View Citation
Seicean A, Alan N, Seicean S, Neuhauser D, Weil RJ. The effect of blood transfusion on short-term, perioperative outcomes in elective spine surgery. J Clin Neurosci. 2014 Sep;21(9):1579-85. doi: 10.1016/j.jocn.2014.03.003. Epub 2014 May 19. — View Citation
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---|---|---|---|---|
Primary | increase of hemoglobin level | 4 weeks |
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