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Clinical Trial Summary

The purpose of this study is to examine the influence of premedication drugs Atropin, Fentanyl and Mivacurium and of endotracheal intubation on cerebral oxygenation and cardiac output in term and preterm newborn infants. Two different protocols of premedication are compared.


Clinical Trial Description

Influence of the following procedures will be examined:

- Application of Atropin

- Application of Fentanyl

- Application of Mivacurium

- possible desaturation and / or bradycardia during intubation attempts

- restoration of arterial oxygen saturation and / or heart rate after succesful intubation

We aim to examine the change of the following parameters by the use of electrical cardiometry:

- stroke volume

- cardiac output

We compare two different premedication protocols and we evaluate the impact of these protocol on the time needed for intubation and on intubation difficulties . ;


Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment


Related Conditions & MeSH terms


NCT number NCT01427985
Study type Interventional
Source University of Ulm
Contact
Status Completed
Phase Phase 4
Start date June 2011
Completion date July 2012

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