Intubation Clinical Trial
Official title:
Comparison of Different Mucoactive Agents for the Care of the Intubated Patient in a Surgical Trauma Intensive Care Unit: A Randomized, Double Blind, Controlled Trial
This study compares N-acetylcysteine (mucomyst) and sodium chloride to determine their efficacy in the prevention of pulmonary mucus obstruction and retention in intubated patients admitted to the surgical trauma intensive care unit (STICU).
Status | Completed |
Enrollment | 260 |
Est. completion date | December 2007 |
Est. primary completion date | |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - Intubated and admitted to the Surgical Trauma Intensive Care Unit (STICU) - Subjects must be eligible to start treatment within 24 hours of their initial intubation Exclusion Criteria: - Patient anticipated to be extubated within 24 hours following STICU admission - Hypersensitivity to acetylcysteine. - Pregnancy |
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Double-Blind, Primary Purpose: Treatment
Country | Name | City | State |
---|---|---|---|
United States | Univesity Hospital | San Antonio | Texas |
Lead Sponsor | Collaborator |
---|---|
The University of Texas Health Science Center at San Antonio |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | prevention of pulmonary mucus obstruction | |||
Secondary | days of mechanical ventilation |
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