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Intubation clinical trials

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NCT ID: NCT05719194 Recruiting - Clinical trials for Mechanical Ventilation

Effect of a Personalized Weaning Strategy on Weaning Success

P-Wean
Start date: February 14, 2023
Phase: N/A
Study type: Interventional

Weaning from mechanical ventilation is a daily challenge in intensive care units, as it can take up to 50% of the total duration of ventilation. The longer the duration of ventilation is, the more there is complication related with it. Even when the spontaneous breathing trial is succeeded, 10 to 20% of extubations are failed and requires re-intubation. There is two different ways to assess if the patient is capable of breathing by its own : T-piece which can be considered as hard to succeed (it can delay extubation for some patients) or pressure support ventilation with no PEEP which can be too easy and lead to an extubation too early. Studies have identified risk factors of weaning induced pulmonary oedema wich is one of the main cause of failed extubation (up to 60%). The purpose of P-WEAN is to evaluate whether a personalized strategy for weaning from mechanical ventilation, including daily search for weaning criteria and individualization of the weaning modality (T-piece or pressure support ventilation with zero PEEP) based on the existence of WIPO risk factors (obesity, COPD, cardiopathy) improves weaning success compared with usual practice.

NCT ID: NCT05515107 Completed - Intubation Clinical Trials

The Laryngoscopic View With C-MAC Videolaryngoscope Miller Blade Lifting the Epiglottis or the Vallecula in Children

Start date: September 1, 2022
Phase: N/A
Study type: Interventional

In this study, the investigators aim to evaluate the glottic visualization and time to intubation during laryngoscopy performed with the C-MAC VL size 1 Miller blade lifting the epiglottis or placing the tip of the blade on the base of the tongue (vallecula) in children younger than 2 years of age.

NCT ID: NCT05428995 Completed - Intubation Clinical Trials

Comparison of Two Videolaryngoscopes (C-MAC vs Airtraq) for Awake Intubation

AWAKECMACTRA
Start date: June 15, 2022
Phase: N/A
Study type: Interventional

Patients with anticipated difficult airway are recommended to be managed with an awake tracheal intubation. Initially fibreoptic bronchoscopy was considered the gold standard, but in the last decade videolaryngoscopes have been demonstrated to be an efficacy alternative technique. Recently, a systematic review and meta-analysis was published investigating the efficacy and safety of videolaryngoscopy compared with fibreoptic bronchoscopy for awake tracheal intubation. Eight prospective, randomized studies were included, with different videolaryngoscopes (C-MAC, GlideScope, Pentax AWS, McGraft, and Bullard). However, a direct comparison of two different videolaryngoscopes for awake tracheal intubation in patients with anticipated difficult airway has not been performed.

NCT ID: NCT05218590 Completed - Intubation Clinical Trials

For Nasotracheal Intubation With Video Rigid Stylet, Which Nostril is Better?

Start date: February 8, 2022
Phase: N/A
Study type: Interventional

To determine which nostril is more suitable for nasotracheal intubation with video rigid stylet.

NCT ID: NCT05197868 Completed - Intubation Clinical Trials

Applied Forces During Neonatal Intubation

Start date: January 20, 2022
Phase: N/A
Study type: Interventional

This study will be to compare the forces applied to mannequin airways (at epiglottis and at palate) during direct laryngoscopy and indirect video laryngoscopy with two kinds of blades (straight blade and hyper-angulated blade)

NCT ID: NCT05164276 Recruiting - Intubation Clinical Trials

Head Position on Pediatric Nasotracheal Intubation

Start date: May 18, 2022
Phase: N/A
Study type: Interventional

The aim of study is to evaluate whether the head position facilitates pediatric nasotracheal intubation when using a video-laryngoscope.

NCT ID: NCT05085743 Completed - Intubation Clinical Trials

Prediction of Endotracheal Tube Depth by Using Deep Convolutional Neural Networks

Start date: November 1, 2019
Phase:
Study type: Observational

Malposition of an endotracheal tube (ETT) may lead to a great disaster. Developing a handy way to predict the proper depth of ETT fixation is in need. Deep convolutional neural networks (DCNNs) are proven to perform well on chest radiographs analysis. The investigators hypothesize that DCNNs can also evaluate pre-intubation chest radiographs to predict suitable ETT depth and no related studies are found. The authors evaluated the ability of DCNNs to analyze pre-intubation chest radiographs along with patients' data to predict the proper depth of ETT fixation before intubation.

NCT ID: NCT05085119 Completed - Clinical trials for Mechanical Ventilation

Validation of the Relationship Between Oxygenation Parameters and ORI™, in Mechanically Ventilated ICU Patients

FiO2RI
Start date: February 9, 2021
Phase: N/A
Study type: Interventional

The ORI™ or Oxygen Reserve Index (Masimo, Irvine, CA, USA) is a non-invasive monitoring system for measuring oxygen reserve. It is a digital sensor (almost identical to the SpO2 sensor) which allows an analysis of the absorption of arterial, venous and capillary components. The measured index, unitless, ranges from 0.00 to 1.00 for moderate hyperoxia levels: from 100 to 200 mmHg. It can alert the clinician to a drop in oxygen stores via the drop in SvO2 before a drop in SpO2 is observed. We propose to carry out a study to elucidate correlation between ORI™ and PaO2.

NCT ID: NCT05008328 Terminated - Clinical trials for Mechanical Ventilation

Feasibility of Music Therapy for Spontaneous Breathing Trials

Start date: August 30, 2021
Phase: N/A
Study type: Interventional

In this study, the investigators will study music therapy for patients during breathing trials, a procedure performed in intensive care units. Participants will be assigned either to standard medical care or standard medical care plus music therapy. Participants have a 50/50 chance (like flipping a coin) of being in either group. In the music therapy group, a board-certified music therapist will sing softly with guitar accompaniment to provide music during the breathing trial. The music is in addition to the usual treatment provided by hospital staff. Participants in the standard medical care group will receive the usual medical care given by hospital staff members. Information will be collected from participant's charts and by observation of vital signs during the breathing trial.

NCT ID: NCT04865081 Recruiting - Intubation Clinical Trials

Clinical Evaluation of an Aerosol Protective Intubation Device on Videolaryngoscopic Intubation Difficulty

Start date: April 19, 2021
Phase: N/A
Study type: Interventional

The VACCIN box, an anti-aerosol intubation box for potential use on COVID-19 (SARS-CoV-2) positive patients, was designed in order to reduce the transmission risk to healthcare workers. This study will compare the safety and the ease of use of the VACCIN box to a standard intubation in healthy participants undergoing elective surgery. It is expected that intubation times and success rate of intubation in the same circumstances will be similar with and without the use of the VACCIN box.