Pressure Over Nasotracheal Intubation Related Nasal Alar Injury

Status Withdrawn

Clinical Trial Summary

Nasotracheal intubation can cause injury and hemorrhage of nasal mucosa and nasal alar. The investigators measure the actual pressure at the angle between nasotracheal tube and nasal alar, analyze the relationship of clinical signs and symptoms to build up optimal clinical routines.

Clinical Trial Description

While assisting ventilation during general anesthesia or other reasons, patients are often intubated with endotracheal tube to secure airway. Endotracheal tube can be placed trans-orally or trans-nasally according to surgical conditions, anatomical considerations and nursing needs. Except inadequate cuff pressure related complication, nasotracheal intubation can cause dysfunction of nasal mucosal cilia, injury and hemorrhage of nasal mucosa, turbinate avulsion, obstruction of nasal airway, sinusitis and compression and injury of nasal alar, resulting in local erythema, ischemia, pressure sore, necrosis, tissue damage and may affect appearance.

Previous studies focus on the process of nasal tracheal intubation, aim to reduce mucosal injury and hemorrhage via specific intubation tool, special endotracheal tube design, lubricant and so on. However, evidences in preventing nasal alar injury are limited, in which injuries are mostly prevented by self-made special endotracheal tube and artificial leather. In general, the etiology of tissue damage is compression pressure exceeding local capillary perfusion pressure, resulting in reduced perfusion, ischemia and necrosis. Clinically, health providers prevent the injury by standardized endotracheal tube fixation and/or artificial leather at sites with potential compression. But the extend of the effect of endotracheal tube to trachea mucosa varies, range of pressure affecting capillary perfusion pressure are not yet defined, and no routine monitoring for dermis compression. Thus, endotracheal tube related skin damage is an important clinical issue without best standard operating procedure.

In this study, the investigators will place a pressure sensor at the angle of nasotracheal tube, measure the actual pressure, define the sites of compression and its pressure, analyze the relationship of clinical signs and symptoms, pressure, and duration of nasotracheal intubation, and build up optimal clinical routines. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03735160
Study type	Observational
Source	Mackay Memorial Hospital
Contact
Status	Withdrawn
Phase
Start date	May 1, 2020
Completion date	December 31, 2023

View Details

See also
Status	Clinical Trial	Phase
Active, not recruiting	`NCT05717907` - Suction Catheter as a Guide for Nasotracheal Intubation Under General Anesthesia	N/A
Completed	`NCT03653910` - Effect-site Concentration of Remifentanil for Double-lumen Tubes Intubation: Airtraq VS Macintosh Laryngoscope	N/A
Recruiting	`NCT04190524` - Sonographic Assessment of Cricoid Pressure	N/A
Completed	`NCT02359370` - The Effects of Lidocaine and Magnesium Sulphate on the Attenuation of the Hemodynamic Response to Tracheal Intubation	Phase 4
Not yet recruiting	`NCT05036460` - Real-time Sonography in Detecting Inadvertent Esophageal Intubation Among Difficult Intubation Patients	N/A
Completed	`NCT05502120` - A Comparison of Vie-Scope and Macintosh Blade Laryngoscopes in Morbidly Obese.	N/A
Completed	`NCT03992950` - Effectiveness of Cricoid and Paratracheal Pressures for Occluding Esophagus	N/A
Completed	`NCT05303948` - Evaluation of Two Positions for Free Floating Tracheal Intubation in Weightlessness	N/A
Completed	`NCT03720093` - Exploratory Analysis of Pulmonary Microbiome in Intubated Patients
Recruiting	`NCT03031808` - Comparison of Two Induction Regimens Using Topical Lidocaine or Muscle Relaxant on Sore Throat and Hemodynamics	Phase 4
Not yet recruiting	`NCT02918526` - Hemodynamic Study With PRAM of the Cardiovascular Response to the Positioning of the Extraglottic Device	N/A
Completed	`NCT02364622` - The Effects of Flexible Intubating Stylet in the Accurate Placement of Double-lumen Endobronchial Tube	N/A
Completed	`NCT05249738` - Tongue Edema Caused by Intubation Tube in Intensive Care Unit Patients
Completed	`NCT03842306` - End-tidal Oxygen Can Reliably Predict the Arterial Partial Pressure of Oxygen Among Emergency Department Patients
Terminated	`NCT03340207` - Novel Airway Device to Aid Endotracheal Intubations	N/A
Recruiting	`NCT05782517` - I-gel vs. Endotracheal Intubation for Laparoscopic Gynaecological Procedures	N/A
Recruiting	`NCT06085326` - Smart Checklist Implementation for Pediatric Tracheal Intubations in the ICU- Multicenter Study	N/A
Active, not recruiting	`NCT06108271` - Innovative Endotracheal Tube Design Reduces Postoperative Laryngeal Injury	N/A
Completed	`NCT05668299` - Determining the Appropriate Setting of an Automated Secretion Removal Technology (TrachFlush)	N/A
Completed	`NCT04079387` - Effect of Endotracheal Tube Plus STYLET Versus Endotracheal Tube Alone	N/A