Intrauterine Growth Retardation Clinical Trial
OBJECTIVES:
I. Determine if mutations in the gene encoding the insulin-like growth factor-I receptor
lead to relative insulin-like growth factor-I insensitivity and produce intrauterine growth
retardation in children.
PROTOCOL OUTLINE:
Patients undergo blood draw. Insulin-like growth factor-I (IGF-I) and insulin-like growth
factor binding protein-3 (IGFBP-3) are measured. Patients whose IGF-I and IGFBP-3 levels are
average or above are tested for the presence of mutation in the insulin-like growth factor-I
receptor.
;
Primary Purpose: Screening
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