Intrauterine Adhesion Clinical Trial
Official title:
The Value of Three-dimensional Ultrasound Applying in Pre and Postoperative Assessment and Prognosis of Intrauterine Adhesions
NCT number | NCT04930913 |
Other study ID # | 2020-1-7027 |
Secondary ID | |
Status | Recruiting |
Phase | |
First received | |
Last updated | |
Start date | July 1, 2020 |
Est. completion date | June 30, 2023 |
In this prospective, multicenter, large-scale study,the investigators wish to examine the accuracy of several three-dimensional ultrasound anatomical and vascular parameters in diagnosing IUA when compared to the gold standard of hysteroscopy,and to assess the value of 3D US applying in prognosis of intrauterine adhesions.
Status | Recruiting |
Enrollment | 600 |
Est. completion date | June 30, 2023 |
Est. primary completion date | June 30, 2022 |
Accepts healthy volunteers | No |
Gender | Female |
Age group | 20 Years to 40 Years |
Eligibility | Inclusion Criteria: - women aged 20-40 - oligomenorrhea or amenorrhea - BMI 18-30 - regular menstruation - written consent obtained Exclusion Criteria: - Hypothalamic amenorrhea, pituitary amenorrhea and ovarian amenorrhea - Patients with uterine fibroids, adenomyosis, uterine malformation and endometrial polyps - Patients with uterine artery embolization - History of endometrial hyperplasia - Irregular menstruation - Patients with severe complications - Patients with hypoovarian function |
Country | Name | City | State |
---|---|---|---|
China | Fu Xing Hospital, Capital Medical University | Beijing |
Lead Sponsor | Collaborator |
---|---|
Fu Xing Hospital, Capital Medical University |
China,
AAGL Elevating Gynecologic Surgery. AAGL practice report: practice guidelines on intrauterine adhesions developed in collaboration with the European Society of Gynaecological Endoscopy (ESGE). Gynecol Surg. 2017;14(1):6. doi: 10.1186/s10397-017-1007-3. Epub 2017 May 1. — View Citation
Amin TN, Saridogan E, Jurkovic D. Ultrasound and intrauterine adhesions: a novel structured approach to diagnosis and management. Ultrasound Obstet Gynecol. 2015 Aug;46(2):131-9. doi: 10.1002/uog.14927. Epub 2015 Jul 20. Review. — View Citation
Carrascosa P, Capuñay C, Vallejos J, Carpio J, Baronio M, Papier S. Two-dimensional and three-dimensional imaging of uterus and fallopian tubes in female infertility. Fertil Steril. 2016 Jun;105(6):1403-1420.e7. doi: 10.1016/j.fertnstert.2016.04.016. Epub 2016 Apr 29. Review. — View Citation
Dreisler E, Kjer JJ. Asherman's syndrome: current perspectives on diagnosis and management. Int J Womens Health. 2019 Mar 20;11:191-198. doi: 10.2147/IJWH.S165474. eCollection 2019. Review. — View Citation
Kim MJ, Lee Y, Lee C, Chun S, Kim A, Kim HY, Lee JY. Accuracy of three dimensional ultrasound and treatment outcomes of intrauterine adhesion in infertile women. Taiwan J Obstet Gynecol. 2015 Dec;54(6):737-41. doi: 10.1016/j.tjog.2015.10.011. — View Citation
Salazar CA, Isaacson K, Morris S. A comprehensive review of Asherman's syndrome: causes, symptoms and treatment options. Curr Opin Obstet Gynecol. 2017 Aug;29(4):249-256. doi: 10.1097/GCO.0000000000000378. Review. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Endometrial volume | Endometrial volume will be measured in in luteal phase by 3D US | 1 year |
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