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Intrauterine Adhesion clinical trials

View clinical trials related to Intrauterine Adhesion.

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NCT ID: NCT05414760 Completed - Clinical trials for Intrauterine Adhesion

Evaluate Formation of IUAs After Third-generation Endometrial Ablation, With and Without Intrauterine Adhesion Barrier

CLEAN
Start date: November 11, 2022
Phase: N/A
Study type: Interventional

Evaluate the formation of adhesions after third-generation endometrial ablation, with and without the intrauterine adhesion barrier.

NCT ID: NCT04824430 Completed - Clinical trials for Intrauterine Adhesion

Assessment of Uterine Access, Uterine Patency and Intrauterine Adhesions Following Endometrial Ablation

Start date: March 23, 2021
Phase:
Study type: Observational

The objective of this study is to gain information concerning the acute and longer-term morphological changes within the uterus following endometrial ablation. Hysteroscopic evaluation of the uterine cavity will be used to determine if physical access and the ability to systematically assess the post-ablation uterine cavity were preserved. The presence, location and severity of intrauterine adhesions will be documented in participants who are 3, 6 and 12 months from their standard of care endometrial ablation.

NCT ID: NCT04381728 Completed - Clinical trials for Intrauterine Adhesion

PREvention of Intrauterine Adhesion After Hysteroscopic Surgery With Novel deGradable Film

PREG1
Start date: November 18, 2019
Phase: N/A
Study type: Interventional

Intrauterine adhesions (IUA) are the major long-term complication of intrauterine procedures and are associated with pelvic pain, menstrual disorders, obstetrical complication and infertility. Womed Leaf is a medical device specifically designed for intrauterine use that prevents intra-uterine adhesions. It is a film that acts as a mechanical barrier to keep uterus walls separated during healing. It is then naturally discharged through the cervix and vagina in less than 30 days. The PREG1 clinical investigation is designed to evaluate Womed Leaf safety under clinical conditions, in women scheduled for a hysteroscopic myomectomy as well as its efficacy.

NCT ID: NCT04308811 Completed - Clinical trials for Intrauterine Adhesion

Autologous Platelet-Rich Plasma in the Management of Asherman Syndrome

Start date: August 10, 2019
Phase: Phase 2
Study type: Interventional

The aim of the study is to find out the benefit of the platelet-rich plasma in preventing reformation of intrauterine adhesions after adhesiolysis in cases of Asherman syndrome

NCT ID: NCT04166500 Completed - Hysteroscopy Clinical Trials

Early Outpatient Hysteroscopy Can Prevent Intrauterine Adhesion After Induced Abortion

Start date: November 1, 2019
Phase: N/A
Study type: Interventional

Background: Intrauterine adhesions are a difficult clinical problem for reproductive infertility. The most common cause is uterine cavity surgery and post-abortion (including abortion and spontaneous abortion). After the abortion, the uterine cavity adhesion, when is the key point, the literature is not much ink, early literature has mentioned that after the abortion, the uterus scraping action is scraped in four days and the uterine adhesion will be smaller than one to four weeks. Much more, it seems that the sooner the uterine adhesion factor is excluded, the more it can reduce uterine adhesion, but the uterine curettage itself is a risk factor for uterine adhesion. This early practice, the current clinical application, is not used, Instead, it is a hysteroscopy. Our past clinical observations, as soon as possible after the abortion, outpatient hysteroscopy, can find the tissue factors that may cause adhesion in the uterine cavity as soon as possible, and immediately remove it with an outpatient hysteroscope. Objective: To verify the early outpatient hysteroscopy and reduce the occurrence of intrauterine adhesion after abortion. Expected benefits to patients: Abortion is likely to cause intrauterine adhesions, which may further cause the incidence of reproductive infertility, should be involved before the formation of permanent injury, reduce the adhesion of the uterine cavity. Outpatient hysteroscopy is a simple and easy-to-use examination procedure that is painless and does not require anesthesia. Although it is invasive but has few complications, it is expected to reduce the occurrence of intrauterine adhesion after abortion.

NCT ID: NCT03724617 Completed - Clinical trials for Intrauterine Adhesion

Clinical Study of Umbilical Cord Mesenchymal Stem Cells Combined With Collagen Scaffold in the Treatment of Thin Endometrium

Start date: October 29, 2018
Phase: N/A
Study type: Interventional

This is a non-blind self-control trial. We mainly compare the changes of endometrial thickness,changes in menstrual flow, and improvement in pregnancy before and after stem cell treatment in patients with thin endometrium.

NCT ID: NCT03578172 Completed - Infertility, Female Clinical Trials

HMG Stimulation Versus HRT for Endometrial Preparation Prior to Blastocyst Transfer in Moderate to Severe IUA Patients

Start date: July 18, 2018
Phase: N/A
Study type: Interventional

Evaluation of endometrial preparation using either human menopausal gonadotrophin (HMG) stimulation and hormone replacement therapy (HRT) prior to blastocyst transfer in patients with moderate to severe intrauterine adhesion (IUA).

NCT ID: NCT03541746 Completed - Clinical trials for Intrauterine Adhesion

The Value of Using Platelet Rich Plasma After Hysteroscopic Lysis of Severe Intrauterine Adhesions

Start date: April 1, 2017
Phase: N/A
Study type: Interventional

The aim of present study is to evaluate the effect of the use of platelet rich plasma in decreasing recurrence of intrauterine adhesions after its lysis.

NCT ID: NCT03353909 Completed - Clinical trials for Intrauterine Adhesion

The Efficacy of A New Crosslinked Hyaluronan Gel in Prevention of Intrauterine Adhesion

Start date: July 1, 2016
Phase: N/A
Study type: Interventional

Using American Fertility Society classification of intrauterine adhesions, the efficacy of a new crosslinked hyaluronan gel in reducing intrauterine adhesion formation after dilatation and curettage for delayed miscarriage in women without previous dilatation and curettage was examined.

NCT ID: NCT03131596 Completed - Clinical trials for Intrauterine Adhesion

Postoperative Intermittent Intrauterine Balloon Dilatation Therapy.

Start date: May 15, 2017
Phase: N/A
Study type: Interventional

In this prospective, randomized, controlled study, the investigators wish to determine the efficacy of intrauterine balloon (IUB) dilatation in the prevention of adhesion reformation when compared with the conventional management.