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PPI Guided Strategies for Prevention and Treatment of Intraoperative Hypotension

Intraoperative Hypotension Clinical Trial

Official title:
Effectiveness of Peripheral Perfusion Index Guided Strategies for the Prevention and Treatment of Hypotension: a Randomized Trial

Clinical Trial Summary

Intraoperative hypotension is closely related to the poor prognosis of surgery. The study is focused on the effectiveness of maintaining normal peripheral perfusion index (PPI) on time-weighted average of hypotension during anesthesia.

Clinical Trial Description

Intraoperative hypotension is closely related to the poor prognosis of surgery. Hypotension decreased blood flow perfusion of organs, which lead to dysfunction of multiple organs, especially increasing serious complications such as cardio-cerebrovascular events and acute renal injury within 30 days after surgery. The aim of this study is to establish a set of strategies that can effectively prevent and treat intraoperative hypotension, so as to alleviate possible harm to patients from perioperative hypotension. The study is focused on the effectiveness of maintaining normal peripheral perfusion index (PPI) on time-weighted average of hypotension during anesthesia. The lower target mean arterial pressure (MAP) was higher than 65 mmHg. MAP less than 65 mmHg was defined as intraoperative hypotension between induction and tracheal extubation. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05792696
Study type Interventional
Source Tongji Hospital
Contact Zhiqiang Zhou, Dr.
Phone 862783663173
Email zqzhou@tjh.tjmu.edu.cn
Status Recruiting
Phase N/A
Start date January 1, 2024
Completion date May 31, 2024
View Details
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