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Perioperative Residual Adrenal Function After Extended Resection for Retroperitoneal Soft Tissue Sarcomas — RAF  

Intraoperative Hypotension Clinical Trial

Official title:
Evaluation of Perioperative Residual Adrenal Function After Extended Multivisceral Resection for Primary Retroperitoneal Soft Tissue Sarcomas: a Prospective Observational Study

Clinical Trial Summary

Early recognition of adrenal function deficit in patients undergoing multivisceral surgery including adrenalectomy for primitive retroperitoneal sarcomas

Clinical Trial Description

The extended multivisceral resection of retroperitoneum is the standard treatment for primary retroperitoneal soft tissue sarcomas. This procedure also includes the removal of the healthy adrenal gland ipsilateral to the tumor site. The investigators think that a such extended surgical approach together with the removal of the adrenal gland may lead to a state of acute adrenal insufficiency and related hemodynamic instability. In order to recognize this condition the investigators use a low dose ACTH test (Synacthen test) during the 1° and 10° post-operative days. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04225494
Study type Observational [Patient Registry]
Source Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Contact
Status Completed
Phase
Start date June 1, 2019
Completion date May 21, 2021
View Details
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