Effect of Hyaluronidase on Intraocular Pressure

Intraocular Pressure Low Clinical Trial

Official title:

Effect of Hyaluronidase on Intraocular Pressure After Retrobulbar Anaesthesia During Cataract Surgery

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT03266406
• Other study ID #: effect of hyaluronidase on IOP
• Status: Not yet recruiting
• Phase: N/A
• First received: August 28, 2017
• Last updated: August 28, 2017
• Start date: September 2017
• Est. completion date: October 2018

Study information

• Verified date: August 2017
• Source: Assiut University
• Contact: Eman Yassin
• Phone: 00201004686028
• Email: emanyassin08[@]gmail.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The aim of this study is to evaluate effect of retrobulbar local anaesthesia after addition of hyaluronidase on IOP during cataract surgery

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 50
• Est. completion date: October 2018
• Est. primary completion date: September 2018
• Accepts healthy volunteers: No
• Gender: All
• Age group: 50 Years to 80 Years

Eligibility

Inclusion Criteria:

• 1-Patients above the age of 50 years. 2-Patients with age related cataract. 3-Normal IOP.

Exclusion Criteria:

• 1History of trauma. 2-Patients with glaucoma. 3-Previous ocular surgery. 4-Patients with other ocular pathology. 5-Uncontrolled diabetes or hypertension. 6-hypersensitivity to lignocaine. 7-Uncooperative or epileptic patients.

Related Conditions & MeSH terms

• Intraocular Pressure Low
• Ocular Hypotension

Intervention

Drug:
• Hyaluronidase
4ml of retrobulbar LA with addition of 15IU/ml hyaluronidase to 2% lidocaine

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Assiut University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	reduction in IOP	reduction of complications of high IOP during surgery	within 10minutes