Clinical Trials Logo

Clinical Trial Summary

This study is to establish a new, alternative stereotactic biopsy frame (AW frame) in the field of stereotactic neurosurgery.


Clinical Trial Description

AW frame is a stereotactic biopsy frame created by Dr. Albert Sii Hieng Wong. A phantom study had completed by Dr. Bik Liang Lau and Dr. Albert Sii Hieng Wong in year 2017 with good accuracy. The phantom study result is going to be submitted for publication by early 2019.

With the good accuracy of AW frame in the phantom study, the frame has been approved by the Medical Research & ethic committee (MREC) for human use in a research setting.

In the study, patient with intracranial lesion which required biopsy, whom fulfilled the criteria will be recruited. All these patient will underwent standard biopsy procedure either under local or general anaesthesia with AW frame mounted.

A localisation CT scanning will be perform with localiser fixed onto the head frame. Target of the intracranial lesion is selected. The coordinates of the localizing points and the selected target inserted into the AW stereo-calculator to generate the AW frame setting up measurements.

Burr hole will be performed and biopsy taken by using Nashold® biopsy needle. An immediate post-biopsy CT imaging will be performed to confirm the site of the biopsy. Patient will be monitored in the neurosurgery ward for any complications.

Histopathologic analysis of the biopsies will be done using usual procedure. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03751085
Study type Interventional
Source Ministry of Health, Malaysia
Contact Bik Liang Lau, MD
Phone +60128822977
Email laubikliang@gmail.com
Status Recruiting
Phase N/A
Start date July 18, 2018
Completion date December 31, 2020

See also
  Status Clinical Trial Phase
Completed NCT03710278 - The Effectiveness and Safety of Human Lumbar Puncture Assist Device (LPat)