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Intestinal Mucosal Barrier clinical trials

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NCT ID: NCT05410665 Recruiting - Sepsis Clinical Trials

The Roles of IL-9/E-cadherin and Ferroptosis in Intestinal Mucosal Barrier Injury in Sepsis

Start date: May 31, 2022
Phase:
Study type: Observational

The investigators aim to evaluate the roles of IL-9/E-cadheirin and ferroptosis in the intestinal mucosal barrier injury of sepsis. The results of this study would lay the foundation for revealing the mechanisms of EEN improving immune imbalance of sepsis and provide a new idea to the early treatment of sepsis.

NCT ID: NCT03791866 Recruiting - Sepsis Clinical Trials

The Th9/IL-9 and Early Enteral Nutrition in Sepsis

Start date: October 1, 2018
Phase: N/A
Study type: Interventional

The investigators aim to evaluate the roles of Th9/IL-9 in the mechanisms of early enteral nutrition (EEN) maintaining intestinal mucosal barrier in sepsis. The results of this study would lay the foundation for revealing the mechanisms of EEN improving immune imbalance of sepsis and provide a new idea to the early treatment of sepsis. In addition, the investigators also aim to evaluate the effects of different proportions of target total enteral nutrition on the prognosis of sepsis.