Clinical Trials Logo

Clinical Trial Summary

The purpose of this study is to determine if patients on long-term olive oil-based parenteral nutrition have an adequate essential fatty acid status and immune status, compared to age- and sex-matched healthy controls.


Clinical Trial Description

Patients, who suffer from severe chronic intestinal failure and whose nutritional intake cannot be met by oral food intake, have as their final option total parenteral nutrition, which contains all necessary macro- and micronutrients. Lipid emulsions are essential for these patients as they are a source of non glucose fuel calories, and they contain (essential) fatty acids which are important as structural component for many cells in the human body. Home parenteral nutrition patients are at risk for essential fatty acid deficiency. Data are lacking that indicate the optimal amount of essential fatty acids required for these patients. The latter seems especially relevant for patients receiving lipid prescriptions which are low in essential fatty acids, like ClinOleic®. Long-term parenteral nutrition dependent patients successfully use ClinOleic®. It is however unknown whether these patient remain to have an adequate essential fatty acid status in the long run. ;


Study Design

Observational Model: Case Control, Time Perspective: Cross-Sectional


Related Conditions & MeSH terms


NCT number NCT01986153
Study type Observational [Patient Registry]
Source Radboud University
Contact
Status Completed
Phase N/A
Start date December 2013
Completion date November 2014

See also
  Status Clinical Trial Phase
Recruiting NCT04733066 - Quality of Life in Patients With Short Bowel Syndrome Treated Without and With Teduglutide - a Prospective Nested Matched Pair Analysis
Recruiting NCT05315765 - Development of a Patient Reported Outcome Measure for GastroIntestinal Recovery
Recruiting NCT04577456 - Chyme Reinfusion for Type 2 Intestinal Failure N/A
Recruiting NCT03590418 - Microbial Diversity of Small Bowel Stoma Effluent and Colonic Faeces
Completed NCT05909228 - Bone Markers in Pediatric IF
Recruiting NCT06283615 - Effect of Vitamin D on Skeletal Muscle Function and Qol in Patients With Chronic Intestinal Failure/Insufficiency N/A
Enrolling by invitation NCT06094504 - Spectral Lighting and Intestinal Failure N/A
Recruiting NCT05902104 - CGM-Assisted Management of PN
Completed NCT01386034 - Effects of Oral Citrulline on Protein Metabolism in Patients With Intestinal Failure (Citrugrêle 2) Phase 3
Recruiting NCT05868785 - Effect of Nocturnal Parenteral Nutrition on Bone Turnover and Energy Metabolism N/A
Terminated NCT01573286 - Safety and Dosing Study of Glucagon-like Peptide 2 (GLP-2) in Infants and Children With Intestinal Failure Phase 1/Phase 2
Active, not recruiting NCT00793195 - Can SMOFlipid®, A Composite Parenteral Nutrition Lipid Emulsion, Prevent Progression Of Parenteral Nutrition Associated Liver Disease In Infants? Phase 2
Recruiting NCT06169774 - Video Training Supplementation for Patients Discharged on Home Parental Nutrition N/A
Completed NCT03222232 - Catheter Salvage in Intestinal Failure Patients N/A
Completed NCT06391762 - Level of Deprivation Assessment in a Population of Short-bowel Syndrome Patients With Intestinal Failure
Completed NCT00995813 - Pilot Study of the Rotavirus Vaccine in Infants With Intestinal Failure Phase 4
Recruiting NCT05813535 - 8.4% Sodium Bicarbonate Locks in Intestinal Failure Phase 2
Completed NCT03869957 - Effect of Parenteral Nutrition With n-3 PUFAs on Patients With Intestinal Failure N/A
Completed NCT00286039 - Plasma Citrulline Level in Relation to Absorptive Surface N/A
Completed NCT01946503 - Infant & Toddler Short Gut Feeding Outcomes Study