Intestinal Epithelial Dysplasia Clinical Trial
Official title:
Characterization Phenotypic and Genetic Study of the Intestinal Epithelial Dysplasia or TE
This PHRC is centred on the intestinal epithelial dysplasia ( DEI) or " tufting enteropathy " or TE the clinical and histo-pathological descriptions of which are specified well to the digestive plan(shot).
The objectives of this PHRC are:
- the phenotypic analysis of the intestinal epithelial dysplasia by clinical and
histo-pathological investigations.
- the identification of proteins involved at the intestinal level in the differentiation,
the proliferation and the membership of the epithelial cells
- from the phenotypic study, a genetic analysis of type maps by homozygote on the whole
genome partner in an approach guided by possible candidate genes
- the study of the genes, chosen according to their location, to their profile of
expression, and to their function in touch with the pathogenic hypotheses
;
Allocation: Non-Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Diagnostic