A Study of Structure and Function of Radial Artery After Transradial Coronary Intervention

Intervention Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02831322
• Other study ID #: 21735
• Status: Completed
• Phase: N/A
• Start date: July 10, 2016
• Est. completion date: October 1, 2017

Study information

• Verified date: February 2023
• Source: The First Hospital of Qinhuangdao
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Several approaches have been proposed to reduce the risk of RAO, including anticoagulation, immediate postprocedural sheath removal, and a small sheath/radial artery ratio. Doppler ultrasound examination showed that interrupted blood flow in RA tend to occur in the proximal end rather than distal part of the artery,which was ignored by a majority of interventional cardiologists. Different insights into occlusion location may lead to different options of sheath materials, models, catheters and puncture access. Thus, the investigators designed this present study to explore the reason of radial artery endothelial dysfuction and damage and occlusion location by flow-mediated dilation (FMD) to determine the suitable method to reduce occlusion risk during TRI.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 600
• Est. completion date: October 1, 2017
• Est. primary completion date: September 5, 2016
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 80 Years

Eligibility

Inclusion Criteria:

• admitted for transradial catheterization.

Exclusion Criteria:

• femoral access, arterial circulatory disease, pathological Allen tests, decompensated heart failure, chronic renal failure

Related Conditions & MeSH terms

• Intervention
• Transradial

Intervention

Procedure:
• Percutaneous coronary intervention
Percutaneous coronary intervention was a nonsurgical technique for treating obstructive coronary artery disease

Locations

Country	Name	City	State
China	Qingsheng wang	Qinhuangdao	Hebei

Sponsors (1)

Lead Sponsor	Collaborator
The First Hospital of Qinhuangdao

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	radial artery occlusion	radial artery occlusion was the absence of a flow signal by Doppler ultrasound examination	6 month