NCT04229212 - Clinical Trial References

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Citation(s)

Tjeenk RM, Peeters MP, van den Ende E, Kastelein GW, Breslau PJ
Wound drainage versus non-drainage for proximal femoral fractures. A prospective randomised study. Injury. 2005 Jan;36(1):100-4.
Varley GW, Milner SA
Wound drains in proximal femoral fracture surgery: a randomized prospective trial of 177 patients. J R Coll Surg Edinb. 1995 Dec;40(6):416-8.
Zhou XD, Wu LD
Reply to Comment on Zhou et al.: Do we really need closed-suction drainage in total hip arthroplasty? A meta-analysis. Int Orthop. 2013 Dec;37(12):2531-2. doi: 10.1007/s00264-013-2125-9. Epub 2013 Oct 11.

Effectiveness of Using Closed-suction Drainage in Treating Proximal Femur Fracture With Cephalomedullary Nail

Clinical trial NCT04229212 - References