ICU Mortality Predictors of Trauma Patients

Intensive Care Unit Clinical Trial

Official title:

Prognostic Effect of Neutrophil \ Lymphocyte Ratio, Lactate Level and Apache 2 Score on Mortality in Intensive Care Trauma Patients at First Hospitalizations

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03894111
• Other study ID #: 2019/32
• Status: Completed
• Start date: January 1, 2019
• Est. completion date: March 27, 2019

Study information

• Verified date: March 2019
• Source: Balikesir University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

In this study, the data of the patients who were hospitalized due to trauma in intensive care unit (ICU) were examined in their first development. The mortality rate and the factors affecting mortality in these patients were determined

Description:

In this study, 107 trauma patients were examined. Patients were divided into two groups according to ICU results: survivors (Group 1) and deceased patients (Group2). Patients were rated in terms of age, Neutrophil lymphocyte ratio (NLR) , mean platelet volüme (MPV), lactat value, intensive care unit stay, APACHE 2 soring systems. Mortality rate and the factors affecting this rate were examined.

83 of the patients were male (77.58%) and 24 were female (22.42%). The mean age was 46 years. The mean value of lactate level was 3.25. MPV mean value was 10.34. NLR mean value was 8.23 and Apache 2 score mean value was 22.8. The average length of stay in hospital was 11.33 days. When the intergroup mortality was evaluated in terms of the relationship between continuous variables, there was a statistically significant difference in apache 2 score. No statistically significant difference was found between age, lactate, MPV, NRL and length of hospital stay.

NRL, MPV, Lactate levels were not suitable for evaluation of trauma patients as a early prognostic factor in the first day ICU admission. The investigators think that the use of trauma scoring systems such as apache 2 related to mortality during first hospitalization in ICU is more appropriate.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 107
• Est. completion date: March 27, 2019
• Est. primary completion date: March 27, 2019
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• trauvma patients

Exclusion Criteria:

• systemic inflammatory diseases

• cancer

• renal failure

• cardiac failure

• serebro vascular diseases

Related Conditions & MeSH terms

• Intensive Care Unit

Intervention

Other:
• decesased patients
mortality ratio

Locations

Country	Name	City	State
Turkey	Balikesir City Hospital	Balikesir

Sponsors (1)

Lead Sponsor	Collaborator
Balikesir University

Country where clinical trial is conducted

Turkey, 

References & Publications (3)

Chen W, Yang J, Li B, Peng G, Li T, Li L, Wang S. Neutrophil to Lymphocyte Ratio as a Novel Predictor of Outcome in Patients With Severe Traumatic Brain Injury. J Head Trauma Rehabil. 2018 Jan/Feb;33(1):E53-E59. doi: 10.1097/HTR.0000000000000320. — View Citation

Dilektasli E, Inaba K, Haltmeier T, Wong MD, Clark D, Benjamin ER, Lam L, Demetriades D. The prognostic value of neutrophil-to-lymphocyte ratio on mortality in critically ill trauma patients. J Trauma Acute Care Surg. 2016 Nov;81(5):882-888. — View Citation

Zahorec R. Ratio of neutrophil to lymphocyte counts--rapid and simple parameter of systemic inflammation and stress in critically ill. Bratisl Lek Listy. 2001;102(1):5-14. English, Slovak. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	mortallty	mortallty ratio	28 days