Injection Site Disorder Clinical Trial
Official title:
Circulating Silicone After Cosmetic Silicone Injection in Transgender Patients
This cross-sectional monocentric study will describe transgender men transitioning into
women and who had cosmetic silicone injection.
The principal objective is to estimate the prevalence of Transgender with circulating
monocytes containing silicone vacuoles in blood smears among Male to Female Transgender
population with a history of cosmetic silicon injections.
The secondary objectives are to describe the transgender population, to describe the
quantity of silicone in vacuoles of circulating monocytes, and the association between
dermatological complications (inflammatory and not inflammatory) and several clinical and
biological characteristics (HIV status, level of immunosuppression, inflammatory syndrome,
quantity of silicone which was injected , silicone quantity in blood smears).
Injectable liquid silicone is a permanent filling product which is no more used in France
because of a high risk of complications. Cosmetic silicone injection is a common
feminization approach for transgender populations.
This cross-sectional monocentric study will describe transgender men transitioning into
women and who had cosmetic silicone injection.
The principal objective is to estimate the prevalence of Transgender with circulating
monocytes containing silicone vacuoles in blood smears among Male to Female Transgender
population with a history of cosmetic silicon injections.
The secondary objectives are to describe the transgender population, to describe the
quantity of silicone in vacuoles of circulating monocytes, and the association between
dermatological complications (inflammatory and not inflammatory) and several clinical and
biological characteristics (HIV status, level of immunosuppression, inflammatory syndrome,
quantity of silicone which was injected , silicone quantity in blood smears).
;
Observational Model: Case-Only, Time Perspective: Cross-Sectional