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Inguinal Hernia clinical trials

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NCT ID: NCT01326039 Recruiting - Inguinal Hernia Clinical Trials

Ultrasound-guided Ilioinguinal-iliohypogastric Block for Inguinal Hernia Repair

Start date: May 2010
Phase: Phase 4
Study type: Interventional

Aim: To investigate whether ultrasound-guided perineural administration of 20 ml bupivacaine 5 mg/ml vs 20 ml isotonic saline at the ilioinguinal-iliohypogastric nerves have a clinically analgesic effect after unilateral open inguinal hernia repair.

NCT ID: NCT01289093 Completed - Inguinal Hernia Clinical Trials

Quality of Life After Laparoscopic Inguinal- Incisional and Umbilical Herniotomy.

life-in
Start date: March 2011
Phase: N/A
Study type: Observational

LIFE-IN. Quality of life after operation for hernias are not well investigated and lack a good and easy-to-understand-tool to measure it. Carolina Comfort Scale (CCS) is a disease-specific quality of life questionnaire, designed by an American group, to monitor quality of life in patients undergoing operation for hernias. The investigators wish to test this questionnaire against Visual Analogue Scale (VAS) scores for core-hernia symptoms, to see if the CCS is a good way to monitor the changes in quality of life and other well-known core-symptoms before and after herniotomies.

NCT ID: NCT01273818 Completed - Inguinal Hernia Clinical Trials

Effectiveness of Topical Antibiotic Prophylaxis in Inguinal Hernia Repair

Start date: January 2011
Phase: Phase 4
Study type: Interventional

Aim of this study is to measure the effectiveness of topical gentamicin to prevent post-operative infection in inguinal tension-free hernia repair operation.Secondary aim is, if it is effective as a prophylactic agent, to compare it's effect with intra venous single dose cefazolin sodium prophylaxis.

NCT ID: NCT01264003 Completed - Inguinal Hernia Clinical Trials

Antibiotic Prophylaxis in Mesh Repair of Inguinal Hernias

Start date: May 2008
Phase: Phase 4
Study type: Interventional

Inguinal hernia repairs is clean surgical procedures. However infection may be a concern when prosthetic materials are used. This prospective randomized study has been set to observe if antibiotic prohylaxis is of benefit in mesh repair of inguinal hernias.

NCT ID: NCT01220024 Completed - Postoperative Pain Clinical Trials

Safety and Efficacy of CollaRx® Bupivacaine Implant in Men After Open Laparotomy Herniorrhaphy

Start date: December 2, 2010
Phase: Phase 2
Study type: Interventional

This study will assess pain intensity for the first 72 hrs after after aggravated movement (cough)following open laparotomy inguinal herniorrhaphy in patient who receive either the CollaRx Bupivacaine implant or a plain collagen sponge.

NCT ID: NCT01203644 Completed - Inguinal Hernia Clinical Trials

Evaluation of the Safety, Efficacy, and Pharmacokinetics of SKY0402 in Subjects Undergoing Inguinal Hernia Repair

Start date: December 2004
Phase: Phase 2
Study type: Interventional

The primary objective of this study was to determine the appropriate dose of SKY0402 for the management of postoperative pain following inguinal hernia repair. This study evaluated the safety, efficacy, and pharmacokinetics of SKY0402 compared with a 100 mg dose of bupivacaine HCl for the treatment of postoperative pain in subjects undergoing inguinal hernia repair. Study drug was administered by surgical wound infiltration at the end of the hernia repair procedure.

NCT ID: NCT01193985 Completed - Inguinal Hernia Clinical Trials

Safety and Performance Study of TIGR Matrix Surgical Mesh in Inguinal Hernia Repair

Start date: April 2009
Phase: N/A
Study type: Interventional

This an open, uncontrolled multicenter clinical study to assess the safety and performance of the WK-6 surgical mesh in adult patients with unilateral inguinal hernia. The primary objective is to determine the safety of the WK-6 surgical mesh. Data will be compared retrospectively with published studies on inguinal hernia mesh. The secondary objectives are to explore the performance of the surgical mesh by measuring the pain pre and post surgery as well as a number of relevant variables for establishing the performance of the mesh. Data will be compared retrospectively with previous studies on inguinal hernia mesh with a follow-up of at least one year.

NCT ID: NCT01170780 Completed - Inguinal Hernia Clinical Trials

Dexamethasone Versus Placebo in Optimizing the Postoperative Period After Laparoscopic Inguinal Hernia Repair

Start date: August 2010
Phase: Phase 3
Study type: Interventional

Does corticosteroid (dexamethasone) have an effect on the postoperative period after laparoscopic hernia repair, when it comes to pain, postoperative nausea and vomiting and convalescence. This randomized, double-blinded study compares dexamethasone versus placebo. The patients are recommended one day of convalescence. The medicine or placebo is given before operation. The patients fill out questionnaire before operation and three hours after operation and in the following three days. The patients also register when they return to normal activities and work.

NCT ID: NCT01117337 Completed - Inguinal Hernia Clinical Trials

Comparing Non-fixation of Mesh to Mesh Fixation in Laparoscopic Inguinal Hernia Repair

Start date: September 2008
Phase: Phase 4
Study type: Interventional

The purpose of the study is 1. To compare the recurrence rate of the laparoscopic total extra peritoneal inguinal hernia repair without fixation of the mesh to mesh fixation under spinal anesthesia 2. To test whether non-fixation of mesh leads to less pain compared to the repair when the mesh is fixed.

NCT ID: NCT01105039 Completed - Inguinal Hernia Clinical Trials

Detailed Pain Pattern After Laparoscopic Inguinal Hernia Repair

Start date: November 2009
Phase: N/A
Study type: Observational

Pain after laparoscopic groin hernia repair consist of different pain components (overall pain, shoulder pain, incisional pain and visceral pain). Thus it is important to find out which of these pain components that is most severe, so intervention can be targeted.