PRICE Survey Of Extubation Following Infratentorial Craniotomy

Infratentorial Neoplasms Clinical Trial

— PRICE1  

Official title:

An International, Multisociety Practice Survey Of Extubation Following Elective Infratentorial Craniotomy In Adult Neurosurgical Patients

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05192733
• Other study ID #: Req-2021-01236
• Status: Completed
• Start date: November 4, 2021
• Est. completion date: February 15, 2022

Study information

• Verified date: March 2022
• Source: Centre Hospitalier Universitaire Vaudois
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The PRICE study primarily aims to identify predictors of early extubation following elective infratentorial craniotomy in adults. It also aims to (i) measure the rate of early extubation in different clinical settings; and (ii) study how the decision to extubate early is made and communicated in clinical practice. The first phase of the study (PRICE1) is a brief online survey addressed to physicians in charge of neurosurgical patients (neuroanesthesiologists, neurosurgeons, neurocritical care specialists) in multiple countries.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 190
• Est. completion date: February 15, 2022
• Est. primary completion date: February 15, 2022
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Physician actively involved in delivering care to neurosurgical patients

• Physician formerly involved in delivering care to neurosurgical patients

Exclusion Criteria:

• Has already completed the survey

Related Conditions & MeSH terms

• Infratentorial Neoplasms

Intervention

Other:
• Survey
This is a cross-sectional practice survey. There is no intervention.

Locations

Country	Name	City	State
Switzerland	Centre Hospitalier Universitaire Vaudois	Lausanne	Vaud

Sponsors (6)

Lead Sponsor	Collaborator
Centre Hospitalier Universitaire Vaudois	Camille Levy, Hervé Quintard, Lien Jakus, Nicolai Goettel, Torstein Meling

Country where clinical trial is conducted

Switzerland, 

References & Publications (2)

Cai YH, Wang HT, Zhou JX. Perioperative Predictors of Extubation Failure and the Effect on Clinical Outcome After Infratentorial Craniotomy. Med Sci Monit. 2016 Jul 12;22:2431-8. — View Citation

Cata JP, Saager L, Kurz A, Avitsian R. Successful extubation in the operating room after infratentorial craniotomy: the Cleveland Clinic experience. J Neurosurg Anesthesiol. 2011 Jan;23(1):25-9. doi: 10.1097/ANA.0b013e3181eee548. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Prevalence of early extubation	Percentage of patients being extubated early, as estimated by responders. Early extubation is defined as extubation at the end of surgery, in the operating room, prior to discharge to recovery or intensive care.	3 months
Secondary	Inventory of perceived main predictors of early extubation	Participants to the survey can select up to 3 of the following options: Survey options are: Patient's level of consciousness Evidence of brainstem dysfunction Patient's physical status prior to surgery History or suspicion of difficult airway Preoperative imaging Duration of surgery Course of surgery Time of day when surgery ends Other (to be completed by responder)	3 months
Secondary	Personnel perceived to make the decision to extubate early	Participants to the survey can select 1 or several of the following options: Anesthesiologist Neurosurgeon Neurocritical care physician	3 months