Influenza, Human Clinical Trial
Official title:
Evaluation of the Effects of Age, Prior Exposure, and Previous Vaccination on the B Cell Response to Inactivated Influenza Vaccine in Healthy Adults and Children
The purpose of this study is to evaluate the immune response in recipients of the vaccine. After participants receive the vaccine, samples of blood will be obtained at several intervals afterwards. These blood samples will be used to measure the immune response to the vaccine. Everyone in this study will receive a single dose of flu vaccine, and have blood samples drawn to measure the immune response over the next 90 days. The investigators will also ask participants to report any flu like illnesses during the flu season, and if participants develop a fever or cough, to come in to be tested for flu. This will allow the investigators to compare the vaccine response between people who got the flu and those who did not.
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