Influenza, Human Clinical Trial
Official title:
Can Uptake of Childhood Influenza Immunisation in GP Practices be Increased Through Behavioural-insight Informed Changes to the Invitation Process?
This study will investigate whether behaviourally informed changes to the invitation process can improve uptake of childhood influenza vaccine by two and three year olds at primary care.
Previous research has shown that small changes to routine invitations/reminders to attend
local health services informed by behavioural science can be used to increase a desired
behaviour (e.g. uptake of health checks, reducing missed appointments).
This trial will determine whether an invitation letter, informed by behavioural insights and
sent through a central system (Child Health Information System, CHIS), can increase uptake of
childhood flu vaccine in primary care.
The trial will take place within the existing national childhood immunisation programme in
the participating area in England. Randomisation will be clustered at the primary care
practice level. Outcome data will be anonymised, routinely collected, individual-level
influenza vaccine uptake data extracted from CHIS. For CHIS data validation purposes,
practice-level vaccine uptake data reported through an alternative, routine system will be
collected. Data will be collected on additional invitations/communications that primary care
practices (in both the intervention and control arms) send to their patients. Cost data for
the centralised letter will also be obtained.
The analysis will investigate the main effect of the intervention on uptake of the flu
vaccination for all eligible children included in the trial. The model will include primary
care practice and Clinical Commissioning Group effects to account for clustering. Secondary
analysis will investigate the impact of such individual factors as age, immunisation history
and socioeconomic status and practice-level factors (e.g. direct communication from
practices) on uptake of the flu vaccination.
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