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Clinical Trial Summary

Participants in this study will be given either CC-42344 (one of two dose levels) or placebo orally for 5 days after receiving an influenza (flu) challenge virus. Participants will not know whether they are getting placebo or CC-42344. The amount of virus in nasal samples will be measured over time. Side effects and pharmacokinetics (the amount of CC-42344 in blood) will also be measured.


Clinical Trial Description

This is a single-center, phase 2a, randomized, double-blind, placebo-controlled study in healthy adult participants. The primary goal of this study is to assess the antiviral activity of orally administered CC-42344 in an influenza human viral challenge model, and to explore the impact of different dose levels on efficacy. In addition, the safety, tolerability, and pharmacokinetics will be assessed. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT06160531
Study type Interventional
Source Cocrystal Pharma, Inc.
Contact Hardeep Johal, BSc
Phone 44 (0)7442 810912
Email h.johal@hvivo.com
Status Recruiting
Phase Phase 2
Start date November 25, 2023
Completion date July 2024

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