Inflammatory Response Clinical Trial
Official title:
"Influence of Fabrication Technique on Microbial Adhesion and Biofilm Formation to Conventional, Milled, and 3D-Printed Resin Denture Base Materials
Verified date | April 2024 |
Source | Menoufia University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
Polymethylmethacrylate (PMMA) has been the material of choice for fabricating complete dentures for more than 80 years now.(1,2) As a material it is easy to handle and can be easily repaired and polished. PMMA while being a low-cost material has good esthetics. Some disadvantages of PMMA as a material are surface roughness and porosities which lead to staining, plaque accumulation and bacterial adhesion over time. Among the various factors that can influence microbial attachment to surfaces, surface roughness, hydrophilicity and free surface energy of PMMA are most important. Carboxylate and methyl ester groups found in PMMA make it a very hydrophilic material with a large amount of free surface energy. Despite the influence of the chemical composition, processing methods play the most important role in developing surface roughness.
Status | Active, not recruiting |
Enrollment | 60 |
Est. completion date | September 5, 2024 |
Est. primary completion date | July 4, 2024 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 30 Years to 70 Years |
Eligibility | Inclusion Criteria: - Completely edentulous populations. - Good physical and mental health. - No systemic disease Exclusion Criteria: - Partially edentulous populations. - Patients with smoking more than 10 citrates day. - Patients with systemic diseases. - Patients undergrown radiotherapy. |
Country | Name | City | State |
---|---|---|---|
Egypt | Mohammed A. El-Sawy | Mansoura |
Lead Sponsor | Collaborator |
---|---|
Menoufia University | Misr University for Science and Technology, Tanta University |
Egypt,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Biofilm formation | such as Candida Albian's and Staphylococcus Aureus colonies per ml | 3 years |
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