Inflammatory Bowel Diseases Clinical Trial
Official title:
Evaluation of Blood Platelet Indices, Platelet Aggregation and Coagulation Profile in the Activity State of Inflammatory Bowel Disease Patients on Biological Treatment
Verified date | June 2022 |
Source | Assiut University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
ulcerative colitis and Crohn's disease, the two major forms of inflammatory bowel disease, are chronic, idiopathic, relapsing inflammatory conditions of the gastrointestinal tract. The mechanism is multifactorial and may result from the combined interaction of environmental, genetic, epithelial barrier defects, dysregulated immune responses, and microbial factors
Status | Not yet recruiting |
Enrollment | 120 |
Est. completion date | October 2024 |
Est. primary completion date | June 5, 2022 |
Accepts healthy volunteers | |
Gender | All |
Age group | 21 Years to 65 Years |
Eligibility | Inclusion Criteria: 1. All patients diagnosed with inflammatory bowel disease ulcerative colitis or crohn's disease 2. All IBD patients received biological treatment 3. All IBD patients controlled with conventional treatment Exclusion Criteria: 1. IBS patients 2. IBD Patients with: a) another autoimmune disease like ITP and SLE B) Bleeding tendency as hemophilia or thrombophilia C) Previous thrombotic events or on anticoagulants or antiplatelet drugs D) With another comorbidity as liver cell failure, respiratory failure, renal failure and cardiac failure |
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
Assiut University |
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | detect of disease activity of IBD patients received biological treatment in the start and in 14 weeks after treatment compared to whose controlled by platelet indices and platelet lymphocytic ratio. | Evaluation of disease activity of IBD patients received biological treatment in the start and in 14 weeks after treatment compared to whose controlled by platelet indices and platelet lymphocytic ratio. | about 14 weeks after start of treatment of inflixmab |
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