Abdominal Ultrasound With Doppler and Peripheral Hemogram in Assesment Inflammatory Bowel Disease

Inflammatory Bowel Diseases Clinical Trial

Official title: Abdominal Ultrasound With Doppler and Peripheral Hemogram in Assesment Inflammatory Bowel Disease

Status Completed

Clinical Trial Summary

assessment of inflammatory bowel disease patients in activity and remission by abdominal ultrasound examine non-invasive and in physiological condition by measuring the colon wall thickness in diagnosis and follow up the patient also including extra intestinal features such as the splanchnic vessels,mesentery and lymph nodes . Doppler u.s can evaluate bowel wall vascularity In activity and remission . peripheral hemogram in relationship to activity inflammatory bowel disease asses anemia ,increase monocyte and decrease mean platelet volume( MPV) . also,the investigator will evaluate the outcome of different lines of treatment traditional and biologic therapy (response to treatment,times of activity and complications)

Clinical Trial Description

the participants will follow up the patient for 1 year in the first visit

All patients in this study will be subjected to:

1. Detailed history.

2. Careful physical examination

3. laboratory investigation

1. complete blood picture.

2. liver function

3. kidney function

4. Iron profile(serum iron ,serum ferritin

5. ESR (erythrocyte sedimentation rate )

g-CRP (C reactive protein) f-LDH (lactate dehydrogenase)

4. Abdominal us(the colon wall thickness,lymph nodes,mass,other organs)

5. Doppler us (mesenteric vessels)

6. colonoscopy after 1 year of treatment follow up every 3 months by abdominal US and peripheral hemogram and last visit after 1 year colonoscopy and biopsy for assessment response to treatment ;

Related Conditions & MeSH terms

• Inflammatory Bowel Diseases
• Intestinal Diseases

• NCT number: NCT03445624
• Study type: Observational [Patient Registry]
• Source: Assiut University
• Status: Completed
• Start date: July 1, 2018
• Completion date: October 1, 2021