Azathioprine & Allopurinol in Inflammatory Bowel Disease Patients

Status Completed

Clinical Trial Summary

Main Study Objectives:

The study is conducted to

- evaluate the minimal allopurinol and azathioprine doses that, in combination, produce therapeutic 6-TGN levels

- evaluate the safety and tolerability of the different allopurinol/azathioprine dose levels

- assess if concomitant allopurinol affects TPMT activity

- assess the clinical efficacy of concomitant allopurinol-azathioprine therapy in the included patients

Clinical Trial Description

n/a

Study Design

Endpoint Classification: Pharmacokinetics/Dynamics Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT00849368
Study type	Interventional
Source	University of Zurich
Contact
Status	Completed
Phase	Phase 1
Start date	January 2009
Completion date	September 2011

View Details

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