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Gene Regulation by Thiazolidinediones — GReaT  

Inflammatory Bowel Disease Clinical Trial

Official title:
Gene Regulation by Thiazolidinediones

Clinical Trial Summary

The purpose of this study is to determine the effect of rosiglitazone on the genes of the colon

Clinical Trial Description

The primary aim of the study is to examine the effect of rosiglitazone (Avandia) on gene regulation in colonic epithelium in the absence of pathologic acute and chronic intestinal inflammation. The secondary aims are to determine the effect of rosiglitazone (Avandia) therapy on T cell activation and cytokine expression in the absence of pathologic acute and chronic intestinal inflammation. ;

Study Design

Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Basic Science

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00567593
Study type Interventional
Source University of Pennsylvania
Contact
Status Completed
Phase Phase 4
Start date October 2007
Completion date March 2008
View Details
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