Infective Endocarditis Clinical Trial
Infective endocarditis (IE) is a rare (30 cases / million / year in France) and serious
disease (20 % of deaths during hospitalization and 40 % after 5 years). The development of an
IE results from the meeting between a bacteremia and a pre-existent heart disorder, most of
the time valvular, allowing the transplant of the circulating bacteria and their
multiplication in the endocardium. Recommendations of prophylactic antibiotic treatment have
been established since 1954 for some medical, particularly dental procedures, at the origin
of bacteremia. But this policy has recently been questioned because its efficacy has not been
demonstrated.
The purpose of this study is identify the situations with risk, by comparing the oral health
status and the hygiene of patients having an IE with oral streptococci to those in patients
having an IE with microorganisms not of oral origin.
It is a case-control observational study. The IE cases are recruited in hospitals
participating to the french prospective observational "EI2008" cohort.
Cases are IE with oral streptococci whereas controls are IE with microorganisms not of oral
origin.
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| Status | Clinical Trial | Phase | |
|---|---|---|---|
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| Active, not recruiting |
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| Not yet recruiting |
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| Completed |
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| Completed |
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|
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| Recruiting |
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