Evaluation of Neuroinflammation in Children With Infantile Spasms

Status Completed

Clinical Trial Summary

The purpose of this study was to investigate the presence of neuroinflammation in children with infantile spasms using 11C-PK11195 positron emission tomography (PK PET) scan, and its response to ACTH treatment by repeating the PK PET scan after treatment.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02092883
Study type	Interventional
Source	Wayne State University
Contact
Status	Completed
Phase	Phase 4
Start date	March 2013
Completion date	July 2017

View Details

See also
Status	Clinical Trial	Phase
Withdrawn	`NCT02299115` - Prednisolone Versus Vigabatrin in the First-line Treatment of Infantile Spasms	Phase 3
Completed	`NCT02885389` - Molecular Genetics in Infantile Spasms	N/A
Completed	`NCT01006811` - Use of the Modified Atkins Diet in Infantile Spasms	Phase 2/Phase 3
Completed	`NCT01828437` - Addition of Pyridoxine to Prednisolone in Infantile Spasms	Phase 3
Recruiting	`NCT01858285` - Genetics of Epilepsy and Related Disorders
Completed	`NCT00552045` - Epilepsy Phenome/Genome Project
Completed	`NCT02220114` - Acceptability Study of a New Paediatric Form of Vigabatrin in Infants and Children With Infantile Spasms or Pharmacoresistant Partial Epilepsy	N/A
Completed	`NCT02954887` - Phase 3 Trial of Cannabidiol (CBD; GWP42003-P) for Infantile Spasms: Open-label Extension Phase (GWPCARE7)	Phase 3
Completed	`NCT01723787` - Genetic Studies in Patients and Families With Infantile Spasms
Withdrawn	`NCT01413711` - An Open-Label, Single and Multiple Oral Dose Pharmacokinetic Study of Vigabatrin in Infants With Infantile Spasms	Phase 4
Completed	`NCT00441896` - A Randomized, Controlled Trial of Ganaxolone in Patients With Infantile Spasms	Phase 2
Terminated	`NCT00442104` - Open-label Extension to Protocol 1042-0500	Phase 2
Withdrawn	`NCT01549288` - Trial of the Modified Atkins Diet in Infantile Spasms Refractory to Hormonal Therapy	Phase 2/Phase 3
Completed	`NCT01575639` - Prednisolone in Infantile Spasms- High Dose Versus Usual Dose	Phase 3
Not yet recruiting	`NCT06315829` - Artificial Intelligence-based Video Analysis to Detect Infantile Spasms
Completed	`NCT01073579` - Sabril Patient Registry	N/A
Completed	`NCT02953548` - Trial of Cannabidiol (CBD; GWP42003-P) for Infantile Spasms (GWPCARE7)	Phase 3
Completed	`NCT00001325` - Metabolic Abnormalities in Children With Epilepsy	N/A
Completed	`NCT00968136` - Short-term Ketogenic Diet as Compared With Conventional Long-term Trial in Refractory Infantile Spasms: A Randomized, Controlled Study	N/A