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Ineffective Esophageal Motility clinical trials

View clinical trials related to Ineffective Esophageal Motility.

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NCT ID: NCT03244553 Completed - Dysphagia Clinical Trials

Treatment of Dysphagia and Ineffective Esophageal Motility With Prucalopride: A Pilot Study

IEMPru
Start date: October 20, 2017
Phase: Phase 2
Study type: Interventional

This study will test prucalopride (a prokinetic drug currently approved by Health Canada for treatment of constipation) as a treatment for Ineffective Esophageal Motility (IEM). Adult patients with previously diagnosed IEM will be invited to participate by the investigators. The participants will take the study medication for 5 days and on the final day of medication undergo an esophageal manometry procedure at the Calgary Gut Motility Centre to measure esophageal function. Symptoms and side effects will be tracked at baseline and on Day 5.

NCT ID: NCT02674412 Completed - Clinical trials for Ineffective Esophageal Motility

Buspirone for Functional Dysphagia

Start date: February 2016
Phase: N/A
Study type: Interventional

This study evaluates the utility of buspirone in patients who have a diagnosis of functional dysphagia. All participants will be randomized to receive either a placebo pill or buspirone. Subsequently, we will evaluate whether their swallowing is improved. Participants who were randomized to receive placebo will then receive buspirone and those who were receiving buspirone will receive placebo. We will again evaluate whether their swallowing improved.