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Safety and Tolerability of Phenylbutyrate in Inclusion Body Myositis

Inclusion Body Myositis Clinical Trial

Official title:
Safety and Tolerability of Phenylbutyrate in Inclusion Body Myositis

Clinical Trial Summary

This is a pilot study (phase 1 clinical trial) to evaluate the safety and tolerability of phenylbutyrate in IBM. In this open label study, 10 patients with sporadic inclusion body myositis will be treated with phenylbutyrate (3 gm twice daily) for 3 months. There will be a run-in period, during which certain biomarkers will be measured at baseline and at the end of the run-in period in addition to final measurement at the end of the treatment period.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04421677
Study type Interventional
Source University of Kansas Medical Center
Contact
Status Completed
Phase Phase 1
Start date August 20, 2020
Completion date January 20, 2022
View Details
See also
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