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NCT02222831 Clinical Trial

Optimizing IVF Treatment - the Impact of Time-lapse Culture and Preimplantation Factor (PIF) on Embryo Development.

In Vitro Fertilization Clinical Trial

Official title:
Optimizing IVF Treatment - the Impact of Time-lapse Culture and Preimplantation Factor (PIF) on Embryo Development.

Clinical Trial Details — Status: Active, not recruiting

Administrative data
NCT number NCT02222831
Other study ID # Skive-2014-BBP
Secondary ID
Status Active, not recruiting
Phase N/A
First received
Last updated
Start date June 2014
Est. completion date December 2022

Study information
Verified date May 2022
Source Regionshospitalet Viborg, Skive
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

The aims of this study are to evaluate: 1. the possible effect of time-lapse culture from day zero (day of oocyte retrieval) on fertilisation rates and embryo quality in standard IVF. 2. the association between PIF status in embryo culture medium and embryo quality assessed by standard subjective parameters and morphokinetic development.

Recruitment information / eligibility
Status Active, not recruiting
Enrollment 100
Est. completion date December 2022
Est. primary completion date January 2016
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Female
Age group 18 Years to 40 Years
Eligibility Inclusion Criteria: - Standard IVF treatment - Body mass Index (BMI) between 18 and 30 - couples in which the male partner has normal sperm concentration and motility according to the World Health Organization (WHO, 2010) Exclusion Criteria: - Patients with less than four oocytes

Study Design

Related Conditions & MeSH terms

Intervention

Procedure:
• Day 0 denudation and time lapse culture on IVF-oocytes.

Locations
Country Name City State
Denmark The Fertility Clinic Skive Skive

Sponsors (1)
Lead Sponsor Collaborator
Regionshospitalet Viborg, Skive

Country where clinical trial is conducted

Denmark, 

Outcome
Type Measure Description Time frame Safety issue
Other Clinical pregnancy rate 7th week of gestation
Primary Embryo Quality Day 0-5 after oocyte pick-up
Secondary Fertilisation rate Day 1 after oocyte pick-up
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