In Vitro Fertilization Clinical Trial
Official title:
To Evaluate The Androgens and Ovary Function Impact on The Pregnancy Outcome in In Vitro Fertilization
Because the society convention is changed, people are late for getting married, leading to
increasing the bearing age in women. According to the previous study, if the age is over 30,
the oocyte number in ovary has left only 10％ and 3％ in over 40 years old. The data is
collected by Bureau of Health Promotion, Department of Health shows that there are about
7000 people treating the infertility and it spends about 150000 to 250000 NT dollars in
every in vitro fertilization (IVF) cycle, but the live birth rate is only 30％. So it is
important to know how to estimate and approve the ovary function that lead to increase the
live birth rate. The investigators plan to estimate the correlation between the serum
androgens levels and pregnancy outcome in the women who have infertility problem.
Furthermore, for the repeated IVF cycle, the ovary function might be re-evlauated because of
the possible effect from stimulated drugs used on previous cycle. It's important to
understand the ovary function for IVF patient to choose the appropriate drugs and dose.
The investigators use blood and clinical test to analyze, the items for analysis are below:
1. Routine blood test: FSH、LH、E2、P4、Anti-Mullerian Hormone(AMH)、
2. Studied blood test: Inhibin B、total testosterone (TT)、Androstenedione、DHEA-S
3. Clinical test: Ultrasound
4. Personal condition. In order to finishing the test, every patient will be asked to
collect about 10 to 15 cc blood for the research.
n/a
Observational Model: Case-Only, Time Perspective: Prospective
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