Using Xenograft Combined With Barrier Membrane to Improve the Formation of

Status Recruiting

Clinical Trial Summary

To evaluate the clinical effect of site preservation after third molars extraction by using tooth extraction of third molars with site preservation using bio-oss and bio-guide in preventing the formation of deep periodontal pockets in the distal of second molars.

Clinical Trial Description

The mandibular third molar is the last tooth to erupt in the dentition, and due to the insufficient eruption position, it can lead to different degrees of impact. During the eruption of impacted tooth, the crown may be partially or completely covered by the gingival flap. A deep blind pocket is formed between the gingival flap and the tooth crown, and food and bacteria are easily impinged in the blind pocket. Under the influence of oral environment and dental plaque, the presence of blind pockets can lead to the loss of periodontal attachment and the absorption of alveolar bone, thus affecting the distal periodontal status of adjacent molars. Organic bone xenograft material composed of absorbable organic bovine hydroxyapatite is one of the commonly used transplantation materials for repairing bone defects. The application effect of allogeneic bone materials in periodontal therapy has been recognized by many experts and scholars. Guided bone regeneration (GBR), as a conventional periodontal bone graft, has achieved good results in periodontal tissue regeneration. Aljuboori et al. found that when the third molar was removed and GBR was performed at the same time, the depth of distal periodontal pocket probing of the adjacent second molar was significantly reduced in the re-examination 6 months after surgery. Hence, this study intends to use xenograft combined with barrier membrane to improve the formation of distal periodontal pocket of the second molars after third molars extraction. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT06318247
Study type	Interventional
Source	The Dental Hospital of Zhejiang University School of Medicine
Contact
Status	Recruiting
Phase	N/A
Start date	June 1, 2023
Completion date	December 30, 2025

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT06023524` - The Effectiveness of Laser Acupuncture and Standard Medication Therapy on Mandibular Post-Odontectomy Patients	N/A
Completed	`NCT02547896` - Effectiveness of Diclofenac and Its Association to Codeine After Lower Third Molar Extraction.	Phase 4
Completed	`NCT05684601` - Impact of 3D Intraoral Scanning on Postsurgical Evaluation of Mandibular Third Molar Surgery	N/A
Completed	`NCT05170516` - The Effect of Saline Irrigation at Different Temperatures on Pain, Edema, and Trismus After Impacted Third Molar Surgery	N/A
Completed	`NCT02481700` - Epidemiological Study on the Surgical Removal of Third Molars
Completed	`NCT05488028` - 3D Evaluation of Facial Swelling Post Impacted Lower Third Molars Surgery: RCT	N/A
Completed	`NCT05679973` - Evaluation of the Efficacy of Polybutester Suture on Postoperative Complications in Lower Impacted Third Molar Surgery	N/A
Recruiting	`NCT03741894` - Examination of the Prevention and Treatment Modalities of Alveolitis in Relation With Impacted Teeth Surgery	Phase 4
Completed	`NCT06017570` - Risk Factors for Distal Caries of Second Molars Adjacent to Mandibular Impacted Third Molars	N/A
Completed	`NCT03894722` - Effects of Polyvinylpyrrolidone Iodine on Postoperative Trismus and Swelling During Impacted Third Molar Surgery	Phase 4
Completed	`NCT02831374` - Effectiveness of Platelet Rich Plasma in Wound Healing	Phase 0
Completed	`NCT02837614` - Evaluation of Preoperative Submucosal Dexamethasone in Third Molar Surgery	Phase 0
Completed	`NCT02494856` - Comparison of the Clinical Efficacy of Naproxen, Associated or Not With Esomeprazol, in Lower Third Molar Removal	Phase 4
Completed	`NCT02450487` - Influence of Genotype of CYP2C9 on Clinical Efficacy and Pharmacokinetics of Piroxicam After Lower Third Molar Surgery	Phase 4
Completed	`NCT05545553` - Piezosurgery and Conventional Rotary Instruments on Third Molar Surgery	N/A
Recruiting	`NCT03619460` - Clinical Efficacy of a New Piezoelectric Technique for Wisdom Teeth Extraction	N/A
Not yet recruiting	`NCT05143359` - Accuracy of Variables for Impacted Mandibular Third Molar Surgery	N/A
Completed	`NCT03784638` - Comparison of Two Different Flap Designs for Bilateral Impacted Mandibular Third Molar Surgery	N/A
Completed	`NCT03752255` - Verbal and Visual Information Techniques on Anxiety in Third Molar Surgery	N/A
Active, not recruiting	`NCT04349579` - Evaluation of the Effects of Irrigation of the Extraction Socket With Rifamycine	Phase 4

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Using Xenograft Combined With Barrier Membrane to Improve the Formation of Deep Periodontal Pockets

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms